LKT Labs

Biochemicals for Life Science Research

Dexamethasone Phosphate Sodium

Dexamethasone Phosphate Sodium

Product ID D1695
Cas No. 2392-39-4
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $75.00 In stock
500 mg $234.20 In stock
1 g $393.30 In stock
Bulk Quote

Quicklinks

Description

Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration and maturation of macrophages. Dexamethasone may also display anti-asthma benefit as well, through the upregulation of PTEN expression. Additionally, dexamethasone is often used in combination with other chemotherapeutics in the treatment of multiple myeloma.

Product Info

Cas No.

2392-39-4
Purity

≥98%
Formula

C22H28FO8PNa2
Formula Wt.

516.40
Chemical Name

(11β, 16α)-9-Fluoro-11,17,21-trihydroxy-16- methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt
IUPAC Name

disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11, 17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
Synonym

Dexamethasone 21-Phosphate Disodium Salt, Ak-Dex, Baldex, Dalalone, Dezone, Hexadrol, Oradexon, Soldesam

Melting Point

238-239°C
Solubility

Soluble in water (500 mg/mL).

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

4°C
Ship Temp

Ambient

Downloads

MSDS

D1695 MSDS PDF
Info Sheet

D1695 Info Sheet PDF

References

Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B8248

    Bumetanide

    Loop diuretic; NKCC symporter and KCC2 co-trans...

    ≥98%
  • P7058

    Protocatechuic Aldehyde

    Polyphenol found in various plants and foods.

    ≥98%
  • A745817

    Asunaprevir

    Antiviral againt SARS-CoV-2

    ≥98%
  • M400220

    MK-2206 Dihydrochloride

    Akt inhibitor.

    ≥99%
  • F4780

    Fluoxetine Hydrochloride

    FIASMA, SERT inhibitor, 5-HT and σ1 antagonist...

    ≥98%
  • T7035

    Triptolide

    Diterpenoid epoxide found in Tripterygium.

    ≥98%
  • C9708

    CYC-116

    AurKB/C inhibitor.

    ≥98%
  • B011458

    Baloxavir

    Cap-dependent endonuclease inhibitor

    ≥ 99%
  • A706840

    ARV-825

    Degrades of BET proteins.

    ≥99%
  • A7460

    Asparaginase

    Catalyzes hydrolysis of asparagine.

    ≥98%
  • L960006

    LY-2606368

    CHK1 inhibitor.

    ≥98%
  • T3038

    Thienylnonanyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥98%
  • C5592

    CNX-774

    BTK inhibitor.

    ≥98%
  • T2934

    Thiamphenicol Palmitate

    Chloramphenicol derivative; protein translation...

    ≥98%
  • T2835

    6-Thioguanine

    Nucleotide (guanine) analog, prevents guanine s...

    ≥90%
  • O6953

    Ornidazole

    5-Nitroimidazole derivative; genotoxic.

    ≥98%
  • G7344

    GSK-2334470

    PI3K and PDK1 inhibitor.

    ≥99%, ≥99%ee
  • N3276

    Nitroso(acetoxymethyl)methylamine

    NNK precursor found in tobacco smoke; carcinoge...

    ≥97%
  • R5661

    Ropinirole Hydrochloride

    Indoline; D2/3 agonist.

    ≥99%
  • T6932

    Triflumizole

    Imidazole; PPARγ agonist, RORγ inverse agonis...

    ≥95%