Dexamethasone Phosphate Sodium

Name: Dexamethasone Phosphate Sodium
SKU: D1695
Availability: InStock

Product ID D1695

Cas No. 2392-39-4

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Dexamethasone is a glucocorticoid that exhibits anti-inflammatory and immunosuppressive activities with minimal mineralocorticoid effect. Under inflammatory conditions, dexamethasone decreases secretion of TNF, IL-6, and IL-1β, inhibiting migration and maturation of macrophages. Dexamethasone may also display anti-asthma benefit as well, through the upregulation of PTEN expression. Additionally, dexamethasone is often used in combination with other chemotherapeutics in the treatment of multiple myeloma.

Product Info

Cas No.	2392-39-4
Purity	≥98%
Formula	C₂₂H₂₈FO₈PNa₂
Formula Wt.	516.40
Chemical Name	(11β, 16α)-9-Fluoro-11,17,21-trihydroxy-16- methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt
IUPAC Name	disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11, 17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate
Synonym	Dexamethasone 21-Phosphate Disodium Salt, Ak-Dex, Baldex, Dalalone, Dezone, Hexadrol, Oradexon, Soldesam
Melting Point	238-239°C
Solubility	Soluble in water (500 mg/mL).
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	4°C
Ship Temp	Ambient

Downloads

MSDS	D1695 MSDS PDF
Info Sheet	D1695 Info Sheet PDF

References

Bartneck M, Peters FM, Warzecha KT, et al. Liposomal encapsulation of dexamethasone modulates cytotoxicity, inflammatory cytokine response, and migratory properties of primary human macrophages. Nanomedicine. 2014 Mar 7. [Epub ahead of print]. PMID: 24607939.

Ni Z, Tang J, Cai Z, et al. A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expression. Respir Res. 2011 Apr 14;12:47. PMID: 21489309.

Morgan G. Future drug developments in multiple myeloma: an overview of novel lenalidomide-based combination therapies. Blood Rev. 2010 Nov;24 Suppl 1:S27-32. PMID: 21126634.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Dexamethasone Phosphate Sodium

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Myriocin

S-(−)-Carbidopa Monohydrate

MLN-4924

Mitotane

Alternariol-9-methyl Ether

Astaxanthin

L-Arginine Ethyl Ester Dihydrochloride

Temocapril Hydrochloride

Mogrol

Adrenomedullin (22-52), human

Recombinant HCV-NS4 Antigens

Atriopeptin II, rat/rabbit/mouse

Dextromethorphan Hydrobromide Hydrate

Kahweol Oleate

PF-07321332

Neuropeptide Y, human/rat

S-(−)-Schisandrin B

G250.A2 Peptide

C59

Caspofungin Diacetate

Footer