Description
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Cas No. | 117830-79-2 |
|---|---|
| Purity | ≥97% |
| Formula | C21H86N3O6 |
| Formula Wt. | 496.57 |
| IUPAC Name | (2S)-2-[[(2S)-1-[2-[[(2S)-1-[(2S)-2-aminopropanoyl]pyrrolidine-2- carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5- (diaminomethylideneamino)pentanoic acid |
| Synonym | APGPR; Procolipase activation peptide. |
| Solubility | Soluble in water (0.7 mg/mL). |
| Appearance | White to off-white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.
Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.
Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.
Mycotoxin contaminant in food and feed.
Imidazole; 14-α demethylase, H+/K+ ATPase, Na+...
Nicotinamide analog prodrug; fatty acid synthet...
Perfluorinated insecticide.
Cephalotaxine alkaloid originally found in Ceph...
K+ channel blocker, catecholamine release stimu...
Methimazole prodrug; thyroid peroxidase inhibit...
NSAID; COX-1/2 inhibitor, potential K+ channel ...
Triterpene sapogenin found in species of Panax;...
FIASMA; α1- and β1/2-adrenergic antagonist.
Macrolide; protein translation inhibitor, mamma...
Synthetic steroid; glucocorticoid agonist.
Semi-synthetic vinca alkaloid found in Catharan...
Triterpene found in species of Citrus; HIV-1 pr...
R-type Ca2+ and voltage-gated Na+ channel block...
Peptide, bee venom toxin; SK2/3/4 K+ channel bl...
Found in Buxus; hERG K+ channel inhibitor.
Diterpene found in Salvia.
Smo inhibitor.
Inhibitor of VEGFR1/2/3.