Description
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Cas No. | 117137-85-6 |
|---|---|
| Purity | ≥98% |
| Formula | C25H4N8O8 |
| Formula Wt. | 582.66 |
| IUPAC Name | 2-[[1-[2-[[1-(2-amino-3-methylbutanoyl)pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid |
| Synonym | VPDPR |
| Solubility | Soluble in water. |
| Appearance | White to off-white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.
Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.
Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.
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