Description
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Product Unit Size | Cost | Quantity | Stock |
|---|
Enterostatin is an endogenous anorexigenic peptide that regulates dietary fat intake and inhibits insulin secretion. Enterostatin binds the F1-ATPase β subunit and decreases serum cholesterol in a CCK-1 receptor-dependent manner.
| Cas No. | 117137-85-6 |
|---|---|
| Purity | ≥98% |
| Formula | C25H4N8O8 |
| Formula Wt. | 582.66 |
| IUPAC Name | 2-[[1-[2-[[1-(2-amino-3-methylbutanoyl)pyrrolidine-2-carbonyl]amino]-3-carboxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid |
| Synonym | VPDPR |
| Solubility | Soluble in water. |
| Appearance | White to off-white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Erlanson-Albertsson C. Fat-Rich Food Palatability and Appetite Regulation. In: Montmayeur JP, le Coutre J, editors. Fat Detection: Taste, Texture, and Post Ingestive Effects. Boca Raton (FL): CRC Press; 2010. Chapter 14. PMID: 21452478.
Takenaka Y, Shimano T, Mori T, et al. Enterostatin reduces serum cholesterol levels by way of a CCK(1) receptor-dependent mechanism. Peptides. 2008 Dec;29(12):2175-8. PMID: 18824202.
Lindqvist A, Berger K, Erlanson-Albertsson C. Enterostatin up-regulates the expression of the beta-subunit of F(1)F(o)-ATPase in the plasma membrane of INS-1 cells. Nutr Neurosci. 2008 Apr;11(2):55-60. PMID: 18510804.
Metabolite of spironolactone; Na+/K+ ATPase par...
Aminoglycoside; protein translation inhibitor.<...
Diterpene found in coffee beans.
Naturally occurring sesteterpenoid.
VEGFR2, PDGFR, FGFR2 inhibitor.
Diterpene alcohol, geranylgeranyl pyrophosphate...
Microtubule polymerization inhibitor.
PKA and PDK1 inhibitor, HCN channel blocker, po...
CDK inhibitor.
MET, VEGFR2, Ron, Axl, FLT3 inhibitor.
Plasminogen inhibitor.
Carotenoid terpene pigment found in various pla...
Niacin derivative.
Endogenous peptide; FPRL1/2 agonist.
NSAID; COX-1/2 inhibitor.
MET and GSK-3α/β inhibitor.
GABA-A agonist, NMDA antagonist, voltage-gated ...
Triazolopyrazine; c-MET inhibitor.
Glycosaminoglycan