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Epimedin C

Epimedin C

Product ID E6134
Cas No. 110642-44-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $97.70 In stock
5 mg $163.40 In stock
10 mg $296.30 In stock
25 mg $612.70 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Epimedin C is a flavonoid originally found in Epimedium sagittatum; it exhibits immunostimulatory and anticancer activities. In hepatoma cells, epimedin C inhibited cellular proliferation by decreasing expression of c-Myc, cyclin D1, and c-fos, and increasing expression of CDK inhibitors p21 and p27. In a mouse model of hydrocortisone acetate-mediated immunosuppression, epimedin C enhances lymphocyte proliferation and increases IL-2 production.

Product Info

Cas No.

110642-44-9

Purity

≥98%

Formula

C39H50O19

Formula Wt.

822.80

Chemical Name

3-[(6-Deoxy-2-O-(6-deoxy-a-L-mannoppyranosyl)-a-L-mannopyranosyl)oxy]-7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one

IUPAC Name

3-[(2S,3R,4R,5R,6S)-4,5-dihydroxy-6-methyl-3-[(2S,3R,4R,5R,6S)-3,4, 5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4- methoxyphenyl)-8-(3-methylbut-2-enyl)-7-[(2S,3R,4S,5S,6R)-3,4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Synonym

Baohuoside VI

Appearance

Yellow Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E6134 MSDS PDF

Info Sheet

E6134 Info Sheet PDF

References

Liu TZ, Chen CY, Yiin SJ, et al. Molecular mechanism of cell cycle blockage of hepatoma SK-Hep-1 cells by Epimedin C through suppression of mitogen-activated protein kinase activation and increased expression of CDK inhibitors p21(Cip1) and p27(Kip1). Food Chem Toxicol. 2006 Feb;44(2):227-35. PMID: 16112786.

Liang HR, Vuorela P, Vuorela H, et al. Isolation and immunomodulatory effect of flavonol glycosides from Epimedium hunanense. Planta Med. 1997 Aug;63(4):316-9. PMID: 9270375.

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