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Erythromycin

Erythromycin

Product ID E6994
Cas No. 114-07-8
Purity ≥94%
Product Unit SizeCostQuantityStock
5 g $71.50 In stock
25 g $204.30 In stock
100 g $385.90 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Erythromycin is a macrolide antibiotic that binds the 50s subunit of bacterial ribosomes, inhibiting protein synthesis by preventing transfer of tRNA from the A site to the P site. This compound displays antibacterial activity against both gram positive and gram negative bacteria; it also inhibits mammalian mRNA splicing.

Product Info

Cas No.

114-07-8

Purity

≥94%

Formula

C37H67NO13

Formula Wt.

733.93

Chemical Name

Erythromycin A

IUPAC Name

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S, 6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12, 13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4, 6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2, 10-dione

Synonym

Abomacetin, Aknin, EMU, E-Mycin, Erymax, Erycen, Erycin.

Melting Point

135-140°C

Solubility

Very slightly soluble in water (~2 mg/ml). Freely soluble in alcohols, acetone, ethyl acetate, acetonitrile or chloroform.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

E6994 MSDS PDF

Info Sheet

E6994 Info Sheet PDF

References

Bermudez L, Sanchez E, Diaz J, et al. Impacts of organic contaminants (erythromycin, ibuprofen, and diclofenac) on the performance of a membrane bioreactor treating urban wastewater: a heterotrophic kinetic investigation. Membranes (Basel). 2023 Jul 27;13(8):697. PMID: 37623758.

Hertweck M, Hiller R, Mueller MW. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. Eur J Biochem. 2002 Jan;269(1):175-83. PMID: 11784311.

Menninger JR, Otto DP. Erythromycin, carbomycin, and spiramycin inhibit protein synthesis by stimulating the dissociation of peptidyl-tRNA from ribosomes. Antimicrob Agents Chemother. 1982 May;21(5):811-8. PMID: 6179465.

Custom Order

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