• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Felodipine

Felodipine

Product ID F1745
Cas No. 72509-76-3
Purity ≥98%
Product Unit SizeCostQuantityStock
50 mg $141.00 In stock
100 mg $225.30 In stock
250 mg $422.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Felodipine is a dihydropyridine antagonist at L-type cardiac Ca2+ channels. Felodipine exhibits antihypertensive, cardioprotective, and anti-inflammatory activities. In rat models of metabolic syndrome, felodipine decreases blood pressure, activation of NF-κB, and levels of serum insulin, ICAM-1, VCAM-1, and circulating macrophages. In animal models of cardiac ischemia/reperfusion, felodipine decreases infarct size.

Product Info

Cas No.

72509-76-3

Purity

≥98%

Formula

C18H19Cl2NO4

Formula Wt.

384.25

IUPAC Name

5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3, 5-dicarboxylate

Synonym

Flodil, Munobal, Penedil, Perfudal, Plendil

Melting Point

142-145°C

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F1745 MSDS PDF

Info Sheet

F1745 Info Sheet PDF

References

Tan HW, Xing SS, Bi XP, et al. Felodipine attenuates vascular inflammation in a fructose-induced rat model of metabolic syndrome via the inhibition of NF-kappaB activation. Acta Pharmacol Sin. 2008 Sep;29(9):1051-9. PMID: 18718174.

Kal JE, Spaan JA, van Wezel HB. Calcium channel blockade with felodipine does not affect metabolic coronary vasodilation in patients with coronary artery disease. J Cardiovasc Pharmacol. 2002 Feb;39(2):225-33. PMID: 11791008.

Koseki N, Deguchi J, Yamashita A, et al. Establishment fo a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish. J Toxicol Sci. 2014 Aug;39(4):579-600. PMID: 25056783.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P0253

    Panaxadiol

    Triterpene sapongenin found in species of Panax...

    ≥98%
  • S8151

    Sumatriptan Succinate

    Tryptamine; 5-HT1B/1D agonist, TRPV1 antagonist...

    ≥99%
  • L5993

    Loxoprofen Sodium Dihydrate

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • G4799

    Glycitin

    Glycosylated isoflavone found in soy; TAS2R ago...

    ≥98%
  • B6902

    B-Raf IN 1

    B-Raf and c-Raf inhibitor.

    ≥98%
  • P0268

    Parasin I

    Histone H2-derived antimicrobial peptide found ...

    ≥95%
  • D3214

    2′,3′-Dideoxyinosine

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • F8150

    Fumonisin B2

    Mycotoxin produced by Fusarium; sphingosine acy...

    ≥97%
  • R0105

    Rabeprazole Sodium

    H+/K+ ATPase and Scpc phosphatase inhibitor.

    ≥98%
  • W317520

    WIN 55,212-2 Mesylate

    Non-selective cannabinoid receptor agonist.

    ≥98%
  • S3584

    Sivelestat Sodium Tetrahydrate

    Neutrophil elastase inhibitor.

    ≥99%
  • K0144

    Kallikrein Inhibitor

    Peptide; serine protease inhibitor.

    ≥95%
  • D0169

    Darifenacin Hydrobromide

    M3 mAChR antagonist.

    ≥98%
  • T0251

    Tamsulosin Hydrochloride

    α1-adrenergic antagonist.

    ≥98%
  • T6934

    Trimebutine Maleate

    L-type Ca2+ channel blocker, BK K+ channel modu...

    ≥96%
  • C2968

    Chrysin

    Flavone found in Passiflora, Oroxylum, and Pleu...

    ≥98%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • C1176

    CCT-128930

    Pyrrolopyrimidine; Akt inhibitor.

    ≥98%
  • W7201

    WS6

    Islet α/β cell proliferation stimulator.

    ≥98%
  • R2714

    Recombinant HCV-NS5 Antigens

    Recombinant HCV antigen fragment.

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only