Description
FHD-286 is a BRG1/BRM ATPase inhibitor, which is associated with tumor development and progression.
Product Unit Size | Cost | Quantity | Stock |
---|
FHD-286 is a BRG1/BRM ATPase inhibitor, which is associated with tumor development and progression.
Cas No. | 2671128-05-3 |
---|---|
Purity | ≥98% |
Formula | C24H30N6O6S2 |
Formula Wt. | 562.66 |
IUPAC Name | N-[(2S)-1-[[4-[6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]pyridin-2-yl]-1,3-thiazol-2-yl]amino]-3-methoxy-1-oxopropan-2-yl]-1-methylsulfonylpyrrole-3-carboxamide |
Synonym | FHD286 |
Appearance | Off white solid |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
Rago F, Rodrigues L, Bonney M, et al. Exquisite sensitivity to dual BRG1/BRM ATPase inhibitors reveals broad SWI/SNF dependencies in acute myeloid leukemia. Mol Cancer Res. 2022 Mar 1;20(3):361-372. PMID: 34799403
Matsubara D, Kishaba Y, Ishikawa S, et al. Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features. Cancer Sci. 2013 Feb;104(2):266-273. PMID: 23163725
Sun A, Tawfik O, Gayed B, et al. Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers. Prostate. 2007 Feb 1;67(2):203-213. PMID: 17075831
Polyphenolic compound present in black tea.
Apoptosis inducing agent.
Peptide, IgG derivative, tuftsin analog.
ITC, used as chiral agent.
Sartan
HDAC inhibitor.
Benzimidazole; microtubule polymerization inhib...
Imidazole; 14-α demethylase, H+/K+ ATPase, Na+...
c-MET and Ron inhibitor.
D-Seco Paclitaxel is an impurity in the product...
Binds to neurotoxin receptor site 2 on voltage-...
Toxin produced by Canarthis vesicatoria; PP1/2A...
Endogenous catecholamine precursor, also found ...
Thiazide-like diuretic; Kv7.1 and minK K+ chann...
β-lactamase inhibitor.
Third generation macrocyclic ALK inhibitor.
Peptide; fibrinolysis inhibitor.
Endogenous glycosaminoglycan that is produced b...
Proteasome inhibitor.
Synthetic progestogen, orexigenic.