Description
Fluconazole is a triazole antifungal compound that inhibits fungal 14-α demethylase. Fluconazole is especially active against Candida and Cryptococcus.
Fluconazole
Product ID F4682
Cas No. 86386-73-4
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 86386-73-4 |
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| Purity | ≥98% |
| Formula | C13H12F2N6O |
| Formula Wt. | 306.27 |
| Chemical Name | α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1- ylmethyl)-1H-1,2,4-triazole-1-ethanol |
| IUPAC Name | 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol |
| Synonym | Biozolene, Diflucan, Elazor, Triflucan |
| Melting Point | 138-140°C |
| Solubility | Slightly soluble in water 1mg/mL. Soluble in ethanol (61mg/mL), ethyl acetate and methanol. DMSO to 100 mM. |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | Ambient |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Cuenca-Estrella M. Antifungal agents in the treatment of systemic infections: Relevance of mechanism of action, activity profile and resistances. Rev Esp Quimioter. 2010 Dec;23(4):169-76. PMID: 21191554.
Mansfield BE, Oltean HN, Oliver BG, et al. Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. PLoS Pathog. 2010 Sep 30;6(9):e1001126. PMID: 20941354.
Matsumoto Y, Miyazaki S, Fukunaga DH, et al. Quantitative evaluation of cryptococcal pathogenesis and antifungal drugs using a silkworm infection model with Cryptococcus neoformans. J Appl Microbiol. 2012 Jan;112(1):138-146. PMID: 22040451.