• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Fluoxetine Hydrochloride

Fluoxetine Hydrochloride

Product ID F4780
Cas No. 56296-78-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $96.00 In stock
5 g $382.10 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Fluoxetine is an SSRI most often used to treat mood or psychiatric disorders such as depression, obsessive compulsive disorder, bulimia nervosa, panic disorder, and PTSD. Fluoxetine inhibits 5-HT reuptake acting as an antagonist at 5-HT transporters (SERTs) as well as at 5-HT receptors and σ1 receptors. Likely related to its antidepressant activities, fluoxetine can prevent cue- and stress-induced reinstatement in animal models of substance abuse. In a clinical setting, fluoxetine increased abstinence rates in former female heroin-dependent subjects when combined with naltrexone compared to naltrexone alone. Additionally, this compound exhibits antiviral activity, demonstrated by its ability to reduce synthesis of coxsackievirus RNA and protein. Fluoxetine also acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

pH value: 5-7 (5% aqueous solution)

Product Info

Cas No.

56296-78-7

Purity

≥98%

Formula

C17H18F3NO • HCl

Formula Wt.

345.79

Chemical Name

N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzene- propanamine hydrochloride

IUPAC Name

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine; hydrochloride

Synonym

Adofen, Fluoxeren, Lovan, Prozac, Sarafem

Melting Point

158.4-158.9°C

Solubility

Soluble in methanol, ethanol, acetone, acetonitrile and chloroform. Water to 10 mM, DMSO to 100 mM. DMF to 16 mg/mL.Ethanol to 69mg/mL

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

F4780 MSDS PDF

Info Sheet

F4780 Info Sheet PDF

References

Zuo J, Quinn KK, Kye S, et al. Fluoxetine is a potent inhibitor of coxsackievirus replication. Antimicrob Agents Chemother. 2012 Sep;56(9):4838-44. PMID: 22751539.

Apparsundaram S, Stockdale DJ, Henningsen RA, et al. Antidepressants targeting the serotonin reuptake transporter act via a competitive mechanism. J Pharmacol Exp Ther. 2008 Dec;327(3):982-90. PMID: 18801947.

Krupitsky EM, Zvartau EE, Masalov DV, et al. Naltrexone with or without fluoxetine for preventing relapse to heroin addiction in St. Petersburg, Russia. J Subst Abuse Treat. 2006 Dec;31(4):319-28. PMID: 17084785.

Pälvimäki EP, Roth BL, Majasuo H, et al. Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2c receptor. Psychopharmacology (Berl). 1996 Aug;126(3):234-40. PMID: 8876023.

Narita N, Hashimoto K, Tomitaka S, et al. Interactions of selective serotonin reuptake inhibitors with subtypes of sigma receptors in rat brain. Eur J Pharmacol. 1996 Jun 20;307(1):117-9. PMID: 8831113.

Opal MD, Klenotich SC, Morais M, et al. Serotonin 2C receptor antagonists induce fast-onset antidepressant effects. Mol Psychiatry. 2014 Oct;19(10):1106-1114. PMID: 24166413.

Nagano M, Liu M, Inagaki H, et al. Early intervention with fluoxetine reverses abnormalities in the serotonergic system and behavior of rats exposed prenatally to dexamethasone. Neuropharmacology. 2012 Aug;63(2):292-300. PMID: 22710353.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R3373

    Risedronate Sodium Hydrate

    Bisphosphonate; inhibits transfer of farnesyl p...

    ≥98%
  • A5162

    Amprolium Hydrochloride

    Thiamine, coccidiostat; thiamine transporter in...

    ≥97%
  • I1418

    Idebenone

    Synthetic quinone CoQ analog, promotes mitochon...

    ≥98%
  • R8179

    Rutaecarpine, synthetic

    Found in Evodia rutaecarpa; potential cAMP, 3β...

    ≥98%
  • S9755

    (R)-Synephrine

    Synephrine is an endogenous alkaloid.

    ≥98%
  • N3213

    Nidulal

    Sesquiterpene found in Nidula.

    ≥95%
  • S7870

    Streptozocin

    Nitrosourea-amino sugar conjugate, DNA cross-li...

    ≥98%
  • C4532

    Clindamycin Hydrochloride

    Lincosamide; ribosomal translocation and protei...

    ≥98%
  • E6997

    Erythropoietin, Human Recombinant

    Endogenous glycoprotein hormone involved in red...

    ≥97%
  • L8262

    Lupinine

    Alkaloid found in species of Loranthus, Calia, ...

    ≥98%
  • M188776

    9-(Methylsulfonyl)nonanyl nitrile

    Synthetic nitrile compound

    ≥98%
  • V1810

    Vecuronium Bromide

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • T1953

    Tenovin-3

    Potential p53 activator or SIRT2 inhibitor.

    ≥98%
  • C0253

    Candesartan

    AT1 inhibitor.

    ≥98%
  • O4672

    Olsalazine Sodium

    5-Aminosalicylate prodrug, NSAID; COX-1/2 inhib...

    ≥98%
  • F4582

    Fluocinolone Acetonide

    Synthetic hydrocortisone derivative; glucocorti...

    ≥98%
  • G571344

    (±)-Goitrin

    Reduces production of thyroid hormones

    ≥98%
  • V174459

    Velpatasvir

    Inhibits NS5A

    ≥99%
  • T0105

    Taxol C

    Taxane synthesis intermediate.

    ≥95%
  • N3350

    Nimorazole

    Nitroimidazole; hypoxic modifier and radiosensi...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only