Description
GDC-6036 is a KRAS G12C covalent inhibitor.
Product Unit Size | Cost | Quantity | Stock |
---|
GDC-6036 is a KRAS G12C covalent inhibitor.
Cas No. | 2417987-45-0 |
---|---|
Purity | ≥98% |
Formula | C29H32ClF4N7O2 |
Formula Wt. | 622.07 |
IUPAC Name | 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]quinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one |
Synonym | GDC6036 |
Appearance | White powder |
Store Temp | -20°C |
---|---|
Ship Temp | Ambient |
Info Sheet |
---|
Cascetta P, Marinello A, Lazzari C, et al. KRAS in NSCLC: state of the art and future perspectives. Cancers (Basel). 2022 Nov 4;14(21):5430. PMID: 36358848
NSAID; COX-1/2 inhibitor, potential K+ channel ...
Endogenous peptide hormone, involved in cell gr...
p110γ PI3K inhibitor, potential TRPC1/5/6 nega...
pan-Bcr-Abl tyrosine kinase inhibitor.
Endogenous peptide, involved in stress signalin...
JAK2 inhibitor, potential EGFR inhibitor.
Pt-based DNA cross-linker.
SIRT2 inhibitor.
Endogenous peptide hormone inolved in gastric e...
Glucocorticoid
Diterpene found in brewed, unfiltered coffee; F...
Lignin found in Sesamin indicum;
Anxiolytic-like agent that stimulates angiogene...
Allylbenzene found in spices and umbelliferous ...
CDK2/4/6 inhibitor
Type A trichothecene mycotoxin produced by Fusa...
Atazanavir metabolite; HIV protease inhibitor.<...
Fluoroquinolone; topoisomerase IV, topoisomeras...
PDK1 and Akt inhibitor.
Major metabolite of ginsenosides Rb1, Rb2, Rc, ...