Description
GDC-6036 is a KRAS G12C covalent inhibitor.
| Product Unit Size | Cost | Quantity | Stock |
|---|
GDC-6036 is a KRAS G12C covalent inhibitor.
| Cas No. | 2417987-45-0 |
|---|---|
| Purity | ≥98% |
| Formula | C29H32ClF4N7O2 |
| Formula Wt. | 622.07 |
| IUPAC Name | 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]quinazolin-4-yl]-3-methylpiperazin-1-yl]prop-2-en-1-one |
| Synonym | GDC6036 |
| Appearance | White powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Cascetta P, Marinello A, Lazzari C, et al. KRAS in NSCLC: state of the art and future perspectives. Cancers (Basel). 2022 Nov 4;14(21):5430. PMID: 36358848
MEK1/2 and ERK inhibitor.
Glycosaminoglycan
Sesquiterpene lactone found in Ginkgo; GABA-A a...
SMAC mimetic; PXR agonist, IAP inhibitor.
ALK inhibitor.
FIASMA, L-type Ca2+ channel blocker, D2 antagon...
Polyphenol found in various plant sources, resv...
NSAID; NMDA inverse agonist, T-type Ca2+ and Cl...
Flavonol found in fruits and vegetables; COMT i...
JAK1/2/3 inhibitor.
Synthetic steroid hormone, estrogen analog, use...
COVID-19 research
SYK/JAK inhibitor
Recombinant HIV-1 glycoprotein antigen fragment...
Imaging agent; Maillard reaction inhibitor.
Shellfish toxin produced by dinoflagellates and...
Mycotoxin produced by Aspergillus; BK K+ channe...
Nitrogen mustard, DNA alkylator.
TRPM8 activator, TRPV3 blocker.
5-HT1A agonist, D2, 5-HT1D antagonist.