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Gentamycin is an aminoglycoside antibiotic originally produced by Micromonospora. Gentamycin binds the ribosomal 30S subunit, preventing formation of the initiation complex, suppressing translocation, and inhibiting protein synthesis. Gentamycin displays antibacterial efficacy against some gram positive bacteria and many gram negative bacteria.
| Cas No. | 1405-41-0 |
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| Formula Wt. | 551.73 |
| IUPAC Name | 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid |
| Synonym | Gentamicin C complex sulfate, Alcomicin, Garamycin, Gentacin, Lugacin, Ophtagram, Pangram, Sulmycin |
| Melting Point | 218-237°C |
| Solubility | Soluble in ethylene glycol and formamide. |
| Appearance | White/Almost White Powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Cavallo G, Martinetto P. The mechanism of action of aminoglycosides. G Batteriol Virol Immunol. 1981 Jul-Dec;74(7-12):335-46. PMID: 6182050.
Hahn FE, Sarre SG. Mechanism of action of gentamicin. J Infect Dis. 1969 Apr-May;119(4):364-9. PMID: 4892389.