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Ginsenoside CK is the major metabolite of ginsenosides Rb1, Rb2, Rc, and Rd. Ginsenoside CK has been shown to suppress growth and inhibit migration of glioblastoma cells. In addition, ginsenoside CK is found to improve glucose intolerance in a rat model, show evidence of neuroprotective and cognition enhancing effects, and decrease the formation of atherosclerotic plaques in a mouse model.
| Cas No. | 39262-14-1 |
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| Purity | ≥98% |
| Formula | C36H62O8 |
| Formula Wt. | 622.88 |
| Chemical Name | Ginsenoside K |
| IUPAC Name | (2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| Synonym | Ginsenoside Compound K; Ginsenoside C-K; Ginsenoside K; 20(S)-Ginsenoside C-K |
| Appearance | White powder |
| Store Temp | 4°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Lee S, Kwon MC, Jang JP, et al. The ginsenoside metabolite compound K inhibits growth, migration and stemness of glioblastoma cells. Int J Oncol. 2017 Aug;51(2):414-424. PMID: 28656196.
Hwang YC, Oh DH, Choi MC, et al. Compound K attenuates glucose intolerance and hepatic steatosis through AMPK-dependent pathways in type 2 diabetic OLETF rats. Korean J Intern Med. 2018 Mar;33(2):347-355. PMID: 28142230.
Oh J, Kim JS. Compound K derived from ginseng: neuroprotection and cognitive improvement. Food Funct. 2016 Nov 9;7(11):4506-4515. PMID: 27801453.
Zhou L, Zheng Y, Li Z, et al. Compound K attenuates the development of atherosclerosis in ApoE(-/-) mice via LXRalpha activation. Int J Mol Sci. 2016 Jul 8;17(7):pii:E1054. PMID: 27399689.