• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Amlodipine

Amlodipine

Product ID A5045
Cas No. 88150-42-9
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $102.00 In stock
5 g $367.30 In stock
10 g $459.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Amlodipine is a dihydropyridine L-type Ca2+ channel blocker that exhibits antihypertensive, anti-anginal, and vasodilatory activities. Amlodipine is clinically used to treat hypertension and angina as it induces relaxation of arterial smooth muscles, decreases blood pressure, and increases blood flow to the heart. Amlodipine also inhibits acid sphingomyelinase (FIASMA), which is involved in programmed cell death. Additionally, this compound improves smooth muscle hypertrophy and collagen deposition, preventing arterial remodeling in hypertensive rats.

Product Info

Cas No.

88150-42-9

Purity

≥98%

Formula

C20H25ClN2O5

Formula Wt.

408.88

Chemical Name

2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4- dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

IUPAC Name

3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1, 4-dihydropyridine-3,5-dicarboxylate

Synonym

UK-48340

Melting Point

134-136°C

Solubility

Soluble in methanol, ethanol (82mg/mL)choroform and DMSO (82mg/mL).

Appearance

Almost White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A5045 MSDS PDF

Info Sheet

A5045 Info Sheet PDF

References

Chen JL, Shang QH, Hu W, et al. Role of TGF-β1/Smads pathway in carotid artery remodeling in renovascular hypertensive rats and prevention by Enalapril and Amlodipine. J Geriatr Cardiol. 2012 Jun;9(2):185-91. PMID: 22916067.

Kornhuber J, Tripal P, Reichel M, et al. Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): a novel pharmacological group of drugs with broad clinical applications. Cell Physiol Biochem. 2010;26(1):9-20. PMID: 20502000.

Wang JG. A combined role of calcium channel blockers and angiotensin receptor blockers in stroke prevention. Vasc Health Risk Manag. 2009;5:593-605. PMID: 19688100.

Fan YY, Kohno M, Nakano D, et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: possible involvement of N-type calcium channel in podocyte. J Hypertens. 2010 May;28(5):1034-1043. PMID: 20411599.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M403007

    MK-3697

    Orexin 2 receptor antagonist

    ≥98%
  • D1631

    Dehydrocorydaline

    Alkaloid compound originally found in Corydalis...

    ≥95%
  • Y0052

    Yangonin

    Dienolide kavalactone originally found in Piper...

    ≥98%
  • M2077

    1-Methoxy-5-methylphenazinium Methyl Sulfate

    Electron carrier used to study dehydrogenase el...

    ≥98%
  • F285081

    Fidaxomicin

    Macrocycle

    ≥98%
  • A0933

    Acitretin

    Retinoid; RARα/β/γ agonist.

    ≥98%, multiple isomers
  • E537331

    Enniatin Complex

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • T1878

    Tetrodotoxin Citrate

    Neurotoxin found in puffer fish; site 1 voltage...

    ≥99%
  • N0075

    Natamycin

    Polyene macrolide; ergosterol inhibitor.

    ≥98%
  • M1745

    Melatonin

    Endogenous hormone involved in circadian rhythm...

    ≥98%
  • V0045

    Valacyclovir Hydrochloride

    Neuraminidase inhibitor.

    ≥98%
  • M1877

    Methylprednisolone

    Synthetic steroid; glucocorticoid agonist.

    ≥96%
  • L960008

    LY-3177833

    Cdc7 inhibitor.

    ≥99%
  • A706840

    ARV-825

    Degrades of BET proteins.

    ≥99%
  • H3272

    His Tag

    Six-histidine peptide used for affinity column ...

    ≥98%
  • A724091

    Asciminib

    Allosteric inhibitor

    ≥98%
  • A4544

    Allyl Disulfide

    Organosulfur found in garlic.

    ≥98%
  • G7340

    GSK-126

    EZH2 HMT inhibitor.

    ≥98%, ≥99%ee
  • D1628

    5,6-Dehydrokawain

    Kavalactone originally found in Piper methystic...

    ≥98%
  • E6470

    Eprinomectin

    Semi-synthetic avermectin; GABA potentiator.

    ≥45%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only