• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Goserelin Acetate

Goserelin Acetate

Product ID G5772
Cas No. 145781-92-6
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $306.70 Please Inquire
2.5 mg $511.20 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Goserelin acts as a peptide agonist at the gonadotropin-releasing hormone (GnRH) or luteinizing hormone releasing hormone (LHRH) receptor, stimulating release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and decreasing androgen levels. Goserelin exhibits anticancer chemotherapeutic benefit, inhibiting cell proliferation and tumor growth in cellular and animal models of prostate cancer, likely through indirect activation of PKC and inhibition of EGFR activity. Goserelin also inhibits cell proliferation and tumor growth in cellular and animal models of ovarian cancer through a mechanism that involves inhibition of Akt phosphorylation. In other animal models, goserelin increases bone elongation.

Product Info

Cas No.

145781-92-6

Purity

≥95%

Formula

C59H84N18O14 C2H4O2

Formula Wt.

1329.48

IUPAC Name

acetic acid;N-[1-[[1-[[1-[[1-[[1-[[1-[[1-[2-[(carbamoylamino)carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Solubility

Soluble in water (20 mg/mL), DMSO.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

G5772 MSDS PDF

Info Sheet

G5772 Info Sheet PDF

Brochures

PI3K-Akt-mTORC Pathway Booklet

References

Detti L, Uhlmann RA, Zhang J, et al. Goserelin fosters bone elongation but does not prevent ovarian damage in cyclophosphamide-treated prepubertal mice. Fertil Steril. 2014 Jan 23. pii: S0015-0282(13)03460-2. [Epub ahead of print]. PMID: 24462062.

Zhang Y, Ding JX, Tao X, et al. Goserelin can inhibit ovarian cancer proliferation and simultaneously protect ovarian function from cisplatin: an in vitro and in vivo study. J Chemother. 2013 Apr;25(2):96-103. PMID: 23684357.

Wells A, Souto JC, Solava J, et al. Luteinizing hormone-releasing hormone agonist limits DU-145 prostate cancer growth by attenuating epidermal growth factor receptor signaling. Clin Cancer Res. 2002 Apr;8(4):1251-7. PMID: 11948140.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L1982

    Leupeptin Hemisulfate

    Protease inhibitor.

    ≥95%
  • T5672

    Tosufloxacin Tosylate

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • H9803

    Hyaluronic Acid Sodium (0.2 -5 kDA)

    Glycosaminoglycan

  • A5061

    Ampalex

    Benzylpiperidine; AMPA potentiator.

    ≥98%
  • A5032

    D,L-Aminoglutethimide

    Aromatase inhibitor.

    ≥98%
  • P1635

    Peiminine

    Steroidal alkaloid found in Fritillaria; M2 mAC...

    ≥98%
  • P3540

    PIK-75 Hydrochloride

    p110α PI3K inhibitor.

    ≥98%
  • B177550

    Benzbromarone

    Non-competitive inhibitor of xanthine oxidase.<...

    ≥99%
  • T5968

    Torsemide

    Loop diuretic; NKCC symporter and HSP90 inhibit...

    ≥99%
  • B4976

    BMS-794833

    MET, VEGFR2, Ron, Axl, FLT3 inhibitor.

    ≥98%
  • S176481

    Semaglutide

    GLP-1 agonist

    ≥95%
  • I7447

    1-Isothiocyanato-6-(methylsulfenyl)-hexane

    Synthetic ITC, erucin analog.

    ≥98%
  • K0053

    Kanamycin A Monosulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • S0930

    Schisantherin A

    Dibenzocyclooctadiene found in Schisandra.

    ≥98%
  • M1677

    11-Methoxyyangonin

    Minor kavalactone originally found in Piper met...

    ≥98%
  • B3577

    Bitertanol

    Pesticide; demethylation inhibitor.

    ≥98%
  • A044176

    Abemaciclib

    CDK inhibitor.

    ≥98%
  • L920000

    LX-2343

    Promotes Aβ clearance.

    ≥98%
  • B030962

    BAY-1251152

    Inhibitor of PTEFb/CDK9.

    ≥98%
  • P7103

    Praziquantel

    Alters membrane permeability and Ca2+ signaling...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only