Description
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
Product Unit Size | Cost | Quantity | Stock |
---|
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
Cas No. | 113276-94-1 |
---|---|
Purity | ≥98% |
Formula | C12H15N3O2S 2HC1 |
Formula Wt. | 338.25 |
Chemical Name | N-(2-(methylamino)ethyl)- dihydrochloride 5-Isoquinolinesulfonamide |
IUPAC Name | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride |
Synonym | H8 dihydrochloride salt |
Appearance | White to off white powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Sui HY, Luan HY, Liu YJ. Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney. Sheng Li Xue Bao. 2012 Aug 25;64(4):449-54. PMID: 22907306.
Hou L, Wang X. PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats. J Neurosci Res. 2001 Nov 15;66(4):592-600. PMID: 11746379.
Benzylpiperidine; AMPA potentiator.
Modified nucleotide used for labeling DNA; DNA ...
Catechol-type flavonoid.
Fetal hemoglobin stimulator; ribonucleotide red...
Thiol prodrug, antioxidant.
BHA derivative, antioxidative food and cosmetic...
Peptide, involved in synapse formation and cell...
PKA substrate.
T-type calcium channel blocker
Antimicrobial peptide found in amphibians.
Phthalide found in celery seeds; COX-1, COX-2, ...
SERCA inhibitor.
L-type Ca2+ channel blocker.
Isoflavone found in Pueraria; 5-HT2C and GABA-A...
Triterpene saponin found in species of Panax.
Alkaloid found in Catharanthus, precursor in sy...
Taxol synthesis intermediate.
Flavonol found in Tagetes.
Polyketide; DNMT 1 inhibitor, RNA synthesis inh...
Staurosporine analog; PKC inhibitor.