Description
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
| Product Unit Size | Cost | Quantity | Stock |
|---|
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
| Cas No. | 113276-94-1 |
|---|---|
| Purity | ≥98% |
| Formula | C12H15N3O2S 2HC1 |
| Formula Wt. | 338.25 |
| Chemical Name | N-(2-(methylamino)ethyl)- dihydrochloride 5-Isoquinolinesulfonamide |
| IUPAC Name | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride |
| Synonym | H8 dihydrochloride salt |
| Appearance | White to off white powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sui HY, Luan HY, Liu YJ. Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney. Sheng Li Xue Bao. 2012 Aug 25;64(4):449-54. PMID: 22907306.
Hou L, Wang X. PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats. J Neurosci Res. 2001 Nov 15;66(4):592-600. PMID: 11746379.
Endogenous purine derivative of xanthine.
Non-opioid analgesic.
Macrolide; protein synthesis inhibitor.
Progesterone derivative; Cyp17A1 inhibitor.
Organosulfide found in Allium; cholesterol synt...
Corticosteroid; glucocorticoid agonist.
Prolyl hydroxylase inhibitor.
β-lactam; penicillin binding protein inhibitor...
Mast cell stabilizer; histamine H1/2/3 antagoni...
NSAID; COX-1/2 inhibitor.
Endogenous peptide involved in vascular contrac...
Synthetic antioxidant that induces phase II enz...
Peptide, tetanus toxin epitope.
Triazole; 14-α demethylase inhibitor, potentia...
Endogenous peptide hormone; motilin agonist.
α1-adrenergic agonist.
Aspirin analog; hemoglobin chain cross-linker.<...
Active metabolite of losartan
Organosulfur found in garlic.
DP1 antagonist.