Description
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
| Product Unit Size | Cost | Quantity | Stock |
|---|
H8 is a nonspecific inhibitor of PKA that modulates Ca2+ signaling pathways.
| Cas No. | 113276-94-1 |
|---|---|
| Purity | ≥98% |
| Formula | C12H15N3O2S 2HC1 |
| Formula Wt. | 338.25 |
| Chemical Name | N-(2-(methylamino)ethyl)- dihydrochloride 5-Isoquinolinesulfonamide |
| IUPAC Name | N-[2-(methylamino)ethyl]isoquinoline-5-sulfonamide;dihydrochloride |
| Synonym | H8 dihydrochloride salt |
| Appearance | White to off white powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Sui HY, Luan HY, Liu YJ. Involvement of protein kinase A activation and phospholipase A(2) inhibition in the adenosine-activated basolateral 50 pS K(+) channels in the thick ascending limb of the rat kidney. Sheng Li Xue Bao. 2012 Aug 25;64(4):449-54. PMID: 22907306.
Hou L, Wang X. PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats. J Neurosci Res. 2001 Nov 15;66(4):592-600. PMID: 11746379.
Statin; HMG-CoA reductase inhibitor, potential ...
Flavonoid found in Rhus verniciflua and Butea m...
PORCN inhibitor.
PI3K and mTOR inhibitor.
Peptide, confers resistance against macrolide a...
ACE inhibitor.
Mycotoxin that has structural similarity to est...
Akt inhibitor.
Endogenous peptide hormone, involved in stress ...
Folic acid analog, derivative of pterin; dihydr...
Camptothecin derivative; topoisomerase I inhibi...
Macrocyclic lactone.
Flavonoid found in various plant sources.
Sulforaphane-cysteine conjugate.
Synthetic peptide; FPRL1 agonist.
Anthracycline, DNA intercalator; topoisomerase ...
Potential PKD binding agent.
Non-steroid; AR antagonist.
SERCA inhibitor.
c-Raf, RET, VEGFR1 inhibitor, potential HMT inh...