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2-Mercaptoethanesulfate sodium (MESNA) is an organosulfur that exhibits mucolytic, immunomodulatory, antioxidative, and cytoprotective activities; it is commonly co-administered with chemotherapeutics and during surgeries to decrease potential cytotoxicity.
| Cas No. | 19767-45-4 |
|---|---|
| Purity | ≥98% |
| Formula | C2H5O3S2 Na |
| Formula Wt. | 164.18 |
| IUPAC Name | sodium;2-sulfanylethanesulfonate |
| Synonym | 2-Mercaptoethanesulfonic acid sodium salt, MESNA |
| Melting Point | >240°C dec. |
| Solubility | Soluble in water (50 mg/mL), DMSO (33 mg/mL). Slightly soluble in alcohol. Practically insoluble in cyclohexane. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Bogiatzi S, Pagonopoulou O, Simopoulou M, et al. The cytogenetic action of ifosfamide, mesna, and their combination on peripheral rabbit lymphocytes: an in vivo/in vitro cytogenetic study. Cytotechnology. 2014 Oct;66(5):753-60. PMID: 23949582.
Vincenti V, Magnan J, Saccardi MS, et al. Chemically Assisted Dissection by Means of Mesna in Cholesteatoma Surgery. Otol Neurotol. 2014 Jul 14. [Epub ahead of print]. PMID: 25025536.
Li X, Yang S, Lv X, et al. The mechanism of mesna in protection from cisplatin-induced ovarian damage in female rats. J Gynecol Oncol. 2013 Apr;24(2):177-85. PMID: 23653836.
