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Ibandronate Sodium Monohydrate

Ibandronate Sodium Monohydrate

Product ID I0502
Cas No. 138926-19-9
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $127.90 In stock
50 mg $255.30 In stock
100 mg $459.60 In stock
Bulk Quote

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  • Description
  • Product Info
  • Shipping and Storage
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  • References
  • Description
  • Product Info
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  • Downloads
  • References
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Description

Ibandronate is a long acting third generation bisphosphonate that exhibits anti-resorptive, anti-osteoporotic, and anti-angiogenic activities. Ibandronate increases bone mineral density, decreases resorption, and prevents fractures and post-menopausal osteoporosis. In vitro, ibandronate increases proliferation of osteoblasts and decreases activity of osteoclasts; it may also inhibit angiogenesis.

Product Info

Cas No.

138926-19-9

Purity

≥98%

Formula

C9H23NO7P2 • H2O • Na

Formula Wt.

359.21

Chemical Name

[1-Hydroxy-3-(methylpentylamino)propylidene]bis- phosphonic acid

IUPAC Name

sodium;hydroxy-[1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl] phosphinate;hydrate

Synonym

Ibandronic acid sodium salt

Melting Point

84°C(dec.)

Solubility

Soluble in water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

I0502 MSDS PDF

Info Sheet

I0502 Info Sheet PDF

References

Ziebart T, Pabst A, Klein MO, et al. Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro. Clin Oral Investig. 2011 Feb;15(1):105-11. PMID: 20024592.

Zhou Q, Zhao ZN, Cheng JT, et al. Ibandronate promotes osteogenic differentiation of periodontal ligament stem cells by regulating the expression of microRNAs. Biochem Biophys Res Commun. 2011 Jan 7;404(1):127-32. PMID: 21108928.

Epstein S, Zaidi M. Biological properties and mechanism of action of ibandronate: application to the treatment of osteoporosis. Bone. 2005 Oct;37(4):433-40. PMID: 16046205.

Custom Order

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