Name: Ifosfamide
SKU: I2056
Availability: InStock

Description

Ifosfamide is a nitrogen mustard alkylator that exhibits anticancer chemotherapeutic activity. Ifosfamide is clinically used to treat various cancers. Because ifosfamide is very cytotoxic, it is often co-administered with cytoprotective agents such as MESNA.

Product Info

Cas No.	3778-73-2
Purity	≥98%
Formula	C₇H₁₅Cl₂N₂O₂P
Formula Wt.	261.09
Chemical Name	N, 3-Bis(2-chloroethyl)-tetrahydro-2H-1,3,2-oxaza- phosphorin-2-amine 2-oxide
IUPAC Name	N,3-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine
Synonym	Holoxan, Ifex, Ifomide, Isoendoxan, Isophosphamide, Mitoxana
Melting Point	39-41°C, 51.0°C
Solubility	Soluble in water.
Appearance	White Crystal Powder

Shipping and Storage

Store Temp	Ambient
Ship Temp	Ambient

Downloads

MSDS	I2056 MSDS PDF
Info Sheet	I2056 Info Sheet PDF

References

Vincenzi B, Frezza AM, Santini D, et al. New therapies in soft tissue sarcoma. Expert Opin Emerg Drugs. 2010 Jun;15(2):237-48. PMID: 20465449.

Nissim I, Horyn O, Daikhin Y, et al. Ifosfamide-induced nephrotoxicity: mechanism and prevention. Cancer Res. 2006 Aug 1;66(15):7824-31. PMID: 16885387.

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Ifosfamide

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