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INCB 28060 Hydrochloride Hydrate

INCB 28060 Hydrochloride Hydrate

Product ID I5206
Cas No. 1865733-40-9
Purity ≥98%
Product Unit SizeCostQuantityStock
5 mg $93.80 In stock
25 mg $234.40 In stock
100 mg $474.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

INCB 28060 (Capmatinib) is an inhibitor of c-MET that exhibits anticancer chemotherapeutic activity. In cellular models of cancer, INCB28060 inhibits cell migration and induces apoptosis, inhibiting proliferation. In animal models, this compound inhibits tumor growth.

Product Info

Cas No.

1865733-40-9

Purity

≥98%

Formula

C23H21Cl2FN6O2

Formula Wt.

503.36

Chemical Name

2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide dihydrochloride hydrate

IUPAC Name

2-Fluoro-N-methyl-4-[7-(6-quinolinylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide dihydrochloride hydrate

Synonym

INC 280 HCl hydrate; Capmatinib Hydrochloride Hydrate; Capmatinib HCl hydrate; capmatinib dihydrochloride monohydrate

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

Info Sheet

I5206 Info Sheet PDF

References

Liu X, Wang Q, Yang G, et al. A novel kinase inhibitor, INCB28060, blocks c-MET-dependent signaling, neoplastic activities, and cross-talk with EGFR and HER-3. Clin Cancer Res. 2011 Nov 15;17(22):7127-38. PMID: 21918175.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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