Description
Isopropyl thiogalactoside is an analog of galactose that is not cleaved by β-galactosidase. Isopropyl thiogalactoside is a mimic of allolactose that induces activation of the lac operon, simulating protein expression.
Isopropyl Thiogalactoside
Product ID I7356
Cas No. 367-93-1
Purity ≥98%
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Product Info
| Cas No. | 367-93-1 |
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| Purity | ≥98% |
| Formula | C9H18O5S |
| Formula Wt. | 238.30 |
| IUPAC Name | (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-propan-2-ylsulfanyloxane-3,4, 5-triol |
| Synonym | Isopropyl β-D-thiogalactoside, IPTG, Isopropyl β-D-1-thiogalactopyranoside |
| Melting Point | 110-114°C |
| Solubility | Soluble in water. |
| Appearance | White flakes |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Yu T, Liu W, Brinck M, et al. Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems. Nat Commun. 2021 Jan 12;12(1):325. PMID: 33436562.
Colarusso A, Lauro C, Calvanese M, et al. Improvement of Pseudoalteromonas haloplanktis TAC125 as a cell factory: IPTG-inducible plasmid construction and strain engineering. Microorganisms. 2020 Sep 24;8(10):1466. PMID: 32987756.
Myung S, Park J, Han J, et al. Development of the mammalian expression vector system that can be induced by IPTG and/or lactose. J Microbiol Biotechnol. 2020 Aug 28;30(8):1124-1131. PMID: 32423185.
Marbach A, Bettenbrock K. lac operon induction in Escherichia coli: Systematic comparison of IPTG and TMG induction and influence of the transacetylase LacA. J Biotechnol. 2012 Jan;157(1):82-8. PMID: 22079752.
Hansen LH, Knudsen S, Sørensen SJ. The effect of the lacY gene on the induction of IPTG inducible promoters, studied in Escherichia coli and Pseudomonas fluorescens. Curr Microbiol. 1998 Jun;36(6):341-7. PMID: 9608745.