Description
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Cas No. | 3520-43-2 |
|---|---|
| Purity | ≥90% |
| Formula | C25H27Cl4IN4 |
| Formula Wt. | 652.23 |
| Chemical Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| IUPAC Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| Solubility | Soluble in methanol, DMSO. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zhang C, Tian Y, Song F, et al. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Sep 8. [Epub ahead of print]. PMID: 26352531.
Jiang Z, Li X, Lin Z, et al. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int J Clin Exp Pathol. 2015 Jul 1;8(7):7774-85. PMID: 26339342.
Smiley ST, Reers M, Mottola-Hartshorn C, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3671-5. PMID: 2023917.
Peptide, tetanus toxin epitope.
Synthetic steroid hormone; AR agonist, ER and P...
Peptide fragment of VSV; LDLR agonist.
TGF-β1 inhibitor.
Endogenous calcitonin-family peptide frgament, ...
Aminoglycoside; protein translation inhibitor.<...
Triazole; 14-α demethylase inhibitor, potentia...
Used for in vitro fertilization; FIASMA, SERM.<...
Antimicrobial peptide found in bee and wasp ven...
Recombinant HIV glycoprotein antigen fragment.<...
Raf inhibitor.
Decreases expression of MMPs, PGE2, and COX-2, ...
Mycotoxin produced by species of Aspergillus; D...
Thienylbutyl ITC analog.
TRPC5, NS4B, histamine H1 inhibitor.
Phenyl hydrazide; neuronal oxidative stress inh...
Trichothecene mycotoxin produced by Fusarium; p...
Caffeic acid derivative.