Description
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Cas No. | 3520-43-2 |
|---|---|
| Purity | ≥90% |
| Formula | C25H27Cl4IN4 |
| Formula Wt. | 652.23 |
| Chemical Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| IUPAC Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| Solubility | Soluble in methanol, DMSO. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zhang C, Tian Y, Song F, et al. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Sep 8. [Epub ahead of print]. PMID: 26352531.
Jiang Z, Li X, Lin Z, et al. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int J Clin Exp Pathol. 2015 Jul 1;8(7):7774-85. PMID: 26339342.
Smiley ST, Reers M, Mottola-Hartshorn C, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3671-5. PMID: 2023917.
Naphthoquinone found in Plumbago.
β-lactam; penicillin binding protein inhibitor...
Minor kavalactone originally found in Piper met...
PDGFR inhibitor.
c-Raf, Ret, VEGFR2 inhibitor, potential STAT3/5...
Mycotoxin produced by Fusarium fungi that infec...
KRAS inhibitor
Purine nucleoside analog; DNA chain terminator,...
Prenylflavinoid, derivative of xanthohumol foun...
Expectorant.
Diterpene alkaloid found in Lagochilus.
Akt inhibitor.
NSAID; COX-1/2 and PDE inhibitor.
Taxane found in Taxus; microtubule depolymeriza...
Folate analog; thymidylate synthase inhibitor.<...
Wortmannin analog; PI3K inhibitor.
Antimicrobial peptide found in Vespula lewisii,...
Resveratrol prodrug; potential SIRT1 activator....
5-HT3 antagonist.
Dipeptide; aminopeptidase (N/CD13) inhibitor.