Description
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Product Unit Size | Cost | Quantity | Stock |
|---|
JC-1 is a potential-dependent J-aggregate-forming cation that is used to detect changes in the mitochondrial membrane potential.
| Cas No. | 3520-43-2 |
|---|---|
| Purity | ≥90% |
| Formula | C25H27Cl4IN4 |
| Formula Wt. | 652.23 |
| Chemical Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| IUPAC Name | 5,6-Dichloro-2-[(1E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-propen-1-yl]-1,3-diethyl-1H-3,1-benzimidazol-3-ium iodide |
| Solubility | Soluble in methanol, DMSO. |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zhang C, Tian Y, Song F, et al. Salinomycin inhibits the growth of colorectal carcinoma by targeting tumor stem cells. Oncol Rep. 2015 Sep 8. [Epub ahead of print]. PMID: 26352531.
Jiang Z, Li X, Lin Z, et al. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int J Clin Exp Pathol. 2015 Jul 1;8(7):7774-85. PMID: 26339342.
Smiley ST, Reers M, Mottola-Hartshorn C, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3671-5. PMID: 2023917.
Ca2+ sensitizer; ATP-sensitive K+ channel activ...
Cyclic depsipeptide is a secondary metabolite i...
Nicotinamide analog prodrug; fatty acid synthet...
Fibrate; PPARα agonist, enoyl-CoA reductase in...
Glucose metabolism inhibitor, N-linked glycosyl...
Dual inhibitor of p70S6K and Akt.
Amide form of vitamin B3 required for productio...
Isoflavone found in legumes such as soy.
Polymer precursor
KRAS inhibitor
Neuromodulator, biomarker
Stilbene, resveratrol analog.
Used for in vitro fertilization; FIASMA, SERM.<...
Natural antibiotic found in Streptomyces parvul...
K+ channel blocker, catecholamine release stimu...
Vinca alkaloid found in Catharanthus; microtubu...
Piperazine; 5-HT1 agonist, 5-HT2/3 and α2-adre...
Iron chelator.
Fluoroquinolone; topoisomerase IV and bacterial...
Endogenous peptide hormone inolved in gastric e...