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Lamivudine

Lamivudine

Product ID L0350
Cas No. 134678-17-4
Purity ≥99%
Product Unit SizeCostQuantityStock
100 mg $61.40 In stock
1 g $78.50 In stock
5 g $168.40 In stock
25 g $472.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Lamivudine is an antiviral compound clinically used as a treatment for hepatitis B infection; it acts as a thymidine analog, inhibiting the reverse transcriptase enzyme. In two separate in vitro models, lamivudine decreased HIV production in recently infected resting cells and inhibited growth of HIV-infected cells at low concentrations. Additionally, lamivudine increases insulin resistance when given with zidovudine in clinical settings.

Product Info

Cas No.

134678-17-4

Purity

≥99%

Formula

C8H11N3O3S

Formula Wt.

229.26

Chemical Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

IUPAC Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Synonym

Epivir, Zeffix, Heptovir

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L0350 MSDS PDF

Info Sheet

L0350 Info Sheet PDF

Brochures

Antivirals Booklet

References

Blümer RM, van Vonderen MG, Sutinen J, et al. Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy. AIDS. 2008 Jan 11;22(2):227-36. PMID: 18097225.

Saavedra-Lozano J, McCoig CC, Cao Y, et al. Zidovudine, lamivudine, and abacavir have different effects on resting cells infected with human immunodeficiency virus in vitro. Antimicrob Agents Chemother. 2004 Aug;48(8):2825-30. PMID: 15273087

Balestrieri E, Forte G, Matteucci C, et al. Effect of lamivudine on transmission of human T-cell lymphotropic virus type 1 to adult peripheral blood mononuclear cells in vitro. Antimicrob Agents Chemother. 2002 Sep;46(9):3080-3. PMID: 12183277.

Custom Order

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