• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
LB-100

LB-100

Product ID L0400
Cas No. 1026680-07-8
Purity ≥98%
Product Unit SizeCostQuantityStock
1 mg $112.60 In stock
5 mg $253.20 In stock
25 mg $810.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

LB-100 is an inhibitor of protein phosphatase 2A (PP2A) that exhibits pro-angiogenic and anticancer activities. LB-100 increases expression of VEGF and HIF-1α. This compound also decreases growth of pancreatic cancer cells and enhances the activity of other co-administered chemotherapeutics in various cancer models.

Product Info

Cas No.

1026680-07-8

Purity

≥98%

Formula

C13H20N2O4

Formula Wt.

268.31

IUPAC Name

3-[(4-Methyl-1-piperazinyl)carbonyl]-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid

Solubility

Water 53 mg/mL DMSO Insoluble Ethanol Insoluble

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

L0400 MSDS PDF

Info Sheet

L0400 Info Sheet PDF

References

Bai X, Zhi X, Zhang Q, et al. Inhibition of protein phosphatase 2A sensitizes pancreatic cancer to chemotherapy by increasing drug perfusion via HIF-1α-VEGF mediated angiogenesis. Cancer Lett. 2014 Dec 28;355(2):281-7. PMID: 25304380.

Bai XL, Zhang Q, Ye LY, et al. Inhibition of protein phosphatase 2A enhances cytotoxicity and accessibility of chemotherapeutic drugs to hepatocellular carcinomas. Mol Cancer Ther. 2014 Aug;13(8):2062-72. PMID: 24867249.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P1917

    Phenylethyl 3-methylcaffeate

    Derivative of methyl caffeate, hydroxycinnamic ...

    ≥97%
  • C8069

    Curcumin

    Diarylheptanoid found in Zingiberaceae.

    ≥97% curcuminoid content
  • A1319

    Adenosine Triphosphate Disodium Hydrate

    Endogenous coenzyme, unit of cellular energy, r...

    ≥95%
  • A7618

    Atenolol

    β1-adrenergic antagonist.

    ≥98%
  • I0417

    R-(−)-Iberin

    Sulforaphane homolog, ITC found in cruciferous ...

    ≥98%
  • G1408

    GDC-0449

    Smo inhibitor.

    ≥98%
  • C3210

    Ciglitazone

    Thiazolidinedione; PPARγ agonist.

    ≥98%
  • H1892

    Hexamethylene Bisacetamide

    HEXIM1 activator.

    ≥99%
  • R3312

    Ridaifen A Dihydrochloride

    Tamoxifen derivative; potential proteasome inhi...

    ≥98%
  • G4782

    Glucoraphenin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • L960004

    LY-404187

    Selective positive allosteric modulator of AMPA...

    ≥98%
  • A7210

    L-(+)-Ascorbic Acid

    Form of vitamin C found in various plant and fo...

    ≥98%
  • P3592

    Pixantrone Dimaleate

    Aza-anthracenedione, DNA intercalator; topoisom...

    ≥98%
  • M577521

    Monascorubrin

    Bulgarialactone azaphilone

    ≥98%
  • G7443

    GSK-429286A

    ROCK1/2 inhibitor, potential RSK and p70S6K inh...

    ≥98%
  • S8098

    SU-1498

    Tyrphostin; VEGFR inhibitor.

    ≥99%
  • T1672

    Terbinafine Hydrochloride

    Allylamine; squalene oxidase and KSR1 inhibitor...

    ≥98%
  • R2811

    Recombinant HIV-1 gp-41

    Recombinant HIV glycoprotein antigen fragment.<...

    ≥95%
  • T1655

    Tenoxicam Impurity 1

    Tenoxicam impurity

    ≥98%
  • I0901

    Icariin

    Flavonol glycoside originally found in Epimediu...

    ≥97%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only