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Litorin

Litorin

Product ID L3577
Cas No. 55749-97-8
Purity ≥95%
Product Unit SizeCostQuantityStock
1 mg $98.40 Please Inquire
2 mg $167.80 Please Inquire
5 mg $294.60 Please Inquire
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Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Litorin is a bombesin-related peptide that binds bombesin receptors in vitro and in vivo. Litorin exhibits anorexigenic and thermo-modulatory activities. In vivo, litorin decreases food intake and body temperature. Litorin also induces contractions in smooth muscle and increases secretion of gastrin and pancreatic polypeptide in animal models. Ex vivo, litorin inhibits thyrotropin-releasing hormone release from the hypothalamus.

Product Info

Cas No.

55749-97-8

Purity

≥95%

Formula

C51H68N14O11S

Formula Wt.

1085.28

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanediamide

Synonym

Ranatesin, 2-de-L-valine-3-de-L-proline-

Solubility

Soluble in acetic acid (1 mg/mL).

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

L3577 MSDS PDF

Info Sheet

L3577 Info Sheet PDF

References

Cline MA, Cofield SA, Tachibana T. Central litorin injection is associated with primary anorexigenic effects that coincide with activation of the magnocellular division of the paraventricular nucleus. Neuropeptides. 2010 Jun;44(3):247-52. PMID: 20116849.

Rouissi N, Rhaleb NE, Nantel F, et al. Characterization of bombesin receptors in peripheral contractile organs. Br J Pharmacol. 1991 May;103(1):1141-7. PMID: 1652341.

Esakov AI, Ashmarin IP, Serova ON, et al. Litorin and litorin-albumin conjugate as effective regulators of body temperature in rats. Biomed Sci. 1990;1(6):610-2. PMID: 2132946.

Mitsuma T, Nogimori T, Sun DH, et al. Litorin (bombesin family) inhibits thyrotropin secretion in rats. Exp Clin Endocrinol. 1986 Jul;87(2):162-8. PMID: 3093255.

Falconieri Erspamer G, Mazzanti G, Farruggia G, et al. Parallel bioassay of litorin and phyllolitorins on smooth muscle preparations. Peptides. 1984 Jul-Aug;5(4):765-8. PMID: 6494026.

Modlin IM, Lamers CB, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin, and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and substance P. Regul Pept. 1981 Jan;1(4):279-88. PMID: 6166964.

Custom Order

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  • This field is for validation purposes and should be left unchanged.

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