• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Loratadine

Loratadine

Product ID L5767
Cas No. 79794-75-5
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $86.80 In stock
1 g $132.30 In stock
5 g $520.60 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Loratadine is a non-sedating antihistaminergic that acts as an antagonist at histamine H1 receptors that exhibits anti-inflammatory, anti-allergic, anti-asthma, and anticancer chemotherapeutic activities. Loratadine is clinically used to treat allergic rhinitis, chronic idiopathic urticaria, and asthma. In vivo, loratadine inhibits growth of colon cancer xenografts through decreases expression of cyclin B1 and Chk1, the induction of G2/M phase cell cycle arrest, and direct damage to DNA. Loratadine also acts as a functional inhibitor of acid sphingomyelinase (FIASMA).

Product Info

Cas No.

79794-75-5

Purity

≥98%

Formula

C22H23ClN2O2

Formula Wt.

382.88

Chemical Name

4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta- [1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

IUPAC Name

ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2, 4-b]pyridin-11-ylidene)piperidine-1-carboxylate

Synonym

Claritin, Lisino

Melting Point

134-136°C

Solubility

Soluble in DMSO (26mg/mL). Insoluble in water.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

L5767 MSDS PDF

Info Sheet

L5767 Info Sheet PDF

References

Soule BP, Simone NL, DeGraff WG, et al. Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines. Radiat Oncol. 2010 Feb 3;5:8. PMID: 20128919.

DuBuske LM. Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. Expert Opin Pharmacother. 2005 Nov;6(14):2511-23. PMID: 16259582.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • P200091

    PF-07104091

    CDK2 inhibitor

    ≥98%
  • T5871

    Torin 2

    Tricyclic benzonaphthyridinone; mTORC1/2 inhibi...

    ≥98%
  • T0109

    13-Acetyl-9-dihydrobaccatin-III

    Found in Taxus, starting material for synthesis...

    ≥98%
  • A5373

    Anisomycin

    Peptidyl transferase inhibitor, protein transla...

    ≥98%
  • M017545

    Manumycin A

    Natural antibiotic found in Streptomyces parvul...

    ≥98%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • R6052

    Recombinant Mycoplasma Pneumonia Antigen

    Pneumonia antigen

  • C179604

    CEP-28122 Mesylate

    ALK inhibitor.

    ≥98%
  • M0262

    Maprotiline Hydrochloride

    Tetracycline; FIASMA, histamine H1, 5-HT2, mACh...

    ≥98%
  • M1877

    Methylprednisolone

    Synthetic steroid; glucocorticoid agonist.

    ≥96%
  • C9708

    CYC-116

    AurKB/C inhibitor.

    ≥98%
  • C0267

    Carnosol

    Diterpene compound originally found in Rosmarin...

    ≥98%
  • I0502

    Ibandronate Sodium Monohydrate

    Bisphosphonate.

    ≥98%
  • A4617

    Aloe Emodin

    Anthraquinone found in aloe; CTFR Cl- channel a...

    ≥98%
  • K5604

    Kobe 0065

    Ras inhibitor.

    ≥99%
  • N0212

    Nedaplatin

    Pt-based DNA cross-linker.

    ≥98%
  • D6108

    1,4-DPCA

    Prolyl hydroxylase inhibitor.

    ≥98%
  • E537334

    Enniatin B

    Mycotoxin contaminant found in cereal grains.

    ≥98%
  • G1849

    Gemifloxacin Mesylate

    Fluoroquinolone; bacterial DNA gyrase inhibitor...

    ≥98%
  • B8176

    2-n-Butylthiophene

    Sulfur analog of furan found in cooked meat pro...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only