Description
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
| Product Unit Size | Cost | Quantity | Stock |
|---|
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
| Cas No. | 603288-22-8 |
|---|---|
| Purity | ≥98% |
| Formula | C28H25FN6O3 |
| Formula Wt. | 512.53 |
| IUPAC Name | 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione |
| Synonym | LY2090314 |
| Solubility | DMSO 100 mg/mL (195.11 mM) Ethanol 2 mg/mL warmed (3.9 mM) Water Insoluble |
| Appearance | Yellow Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, et al. Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure. Drug Metab Dispos. 2013 Apr;41(4):714-26. PMID: 23305709.
JAK2 inhibitor
Bulgarialactone azaphilone
Benzophenanthridine alkaloid, sanguinarine meta...
BCL-XL specific degrader
Phenylpyrazoleanilide; IL-17 production inhibit...
ITC found in cruciferous vegetables, homolog of...
Bisphosphonate.
Actinomycin derivative used to study apoptosis ...
PAK4 inhibitor.
SERM.
Coenzyme, vitamin found in dairy, meat, eggs, f...
Caffeic acid derivative.
Dynamin inhibitor.
Enone.
Prenylated phenolic terpene found in various pl...
Flavonol found in fruits and vegetables; COMT i...
Bisphosphonate; inhibits transfer of farnesyl p...
Naturally produced ITC, sulfonyl analog of sulf...
Macrolide; vacuolar H+-ATPase inhibitor.
Mycotoxin produced by Fusarium fungi that infec...