Description
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
Product Unit Size | Cost | Quantity | Stock |
---|
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
Cas No. | 603288-22-8 |
---|---|
Purity | ≥98% |
Formula | C28H25FN6O3 |
Formula Wt. | 512.53 |
IUPAC Name | 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione |
Synonym | LY2090314 |
Solubility | DMSO 100 mg/mL (195.11 mM) Ethanol 2 mg/mL warmed (3.9 mM) Water Insoluble |
Appearance | Yellow Powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | |
---|---|
Info Sheet |
Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, et al. Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure. Drug Metab Dispos. 2013 Apr;41(4):714-26. PMID: 23305709.
SIRT1/2 inhibitor.
Valsartan impurity
Mouse selective STING agonist.
Ergot derivative found in Claviceps; α1-adrene...
Atypical amino acid found in Isaria sinclairi, ...
Geldanamycin derivative; HSP90 inhibitor.
Triterpene saponin originally found in Bolboste...
pan-Bcr-Abl tyrosine kinase inhibitor.
Iridoid glucoside found in Eucommia, Castilleja...
Non-depolarizing NMJ blocker; nAChR and M2/3 mA...
Triterpenoid
Thiazolidinedione; PPARγ agonist.
Diphenylmethane, inhibits secretion of cortisol...
Dicarboxylic acid found in Arabidopsis; PPARγ ...
Impurity of diclofenac
Mycotoxin produced by Alternaria; topoisomerase...
Fermentation impurity
Endogenous peptide fragment, involved in vasoco...
Natural antibiotic found in Streptomyces parvul...
Found in Aconitum bulleyanum; voltage-gated Na+...