Description
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
| Product Unit Size | Cost | Quantity | Stock |
|---|
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
| Cas No. | 603288-22-8 |
|---|---|
| Purity | ≥98% |
| Formula | C28H25FN6O3 |
| Formula Wt. | 512.53 |
| IUPAC Name | 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione |
| Synonym | LY2090314 |
| Solubility | DMSO 100 mg/mL (195.11 mM) Ethanol 2 mg/mL warmed (3.9 mM) Water Insoluble |
| Appearance | Yellow Powder |
| Store Temp | 4°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, et al. Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure. Drug Metab Dispos. 2013 Apr;41(4):714-26. PMID: 23305709.
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