Description
LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
Product Unit Size | Cost | Quantity | Stock |
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LY2090314 is an inhibitor of glycogen synthase kinase (GSK-3).
Cas No. | 603288-22-8 |
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Purity | ≥98% |
Formula | C28H25FN6O3 |
Formula Wt. | 512.53 |
IUPAC Name | 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione |
Synonym | LY2090314 |
Solubility | DMSO 100 mg/mL (195.11 mM) Ethanol 2 mg/mL warmed (3.9 mM) Water Insoluble |
Appearance | Yellow Powder |
Store Temp | 4°C |
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Ship Temp | Ambient |
MSDS | |
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Info Sheet |
Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, et al. Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure. Drug Metab Dispos. 2013 Apr;41(4):714-26. PMID: 23305709.
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