• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
M2698

M2698

Product ID M002698
Cas No. 1379545-95-5
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $115.90 In stock
5 mg $286.10 In stock
25 mg $729.10 Please Inquire
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

M2698 is a dual inhibitor of p70S6K and Akt. In cancers with dysregulation of the PI3K/Akt/mTOR signaling pathway, M2698 demonstrates tumor growth inhibition, such as in mouse xeongraft models of triple-negative and Her-2 expressing breast cancer cell lines.

Product Info

Cas No.

1379545-95-5

Purity

≥99%

Formula

C21H19ClF3N5O

Formula Wt.

449.86

Chemical Name

4-[[(1S)-2-(azetidin-1-yl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl]amino]quinazoline-8-carboxamide

IUPAC Name

4-({(1S)-2-(1-Azetidinyl)-1-[4-chloro-3-(trifluoromethyl)phenyl]ethyl}amino)-8-quinazolinecarboxamide

Synonym

M 2698, M-2698, MSC-2363318A

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

M002698 MSDS PDF

Info Sheet

M002698 Info Sheet PDF

References

Machl A., Wilker E., et al. M2698 is a potent dual-inhibitor of p70S6K and Akt that affects tumor growth in mouse models of cancer and crosses the blood-brain barrier. Am J Cancer Res. 6(4):806-18 (2016).

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • D1629

    Dehydroepiandrosterone

    Endogenous steroid hormone; ERβ, NMDA, σ1 ago...

    ≥98%
  • L5870

    Lornoxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • P7034

    Prion Peptide (106-126), human

    Synthetic peptide fragment, prion protein analo...

    ≥95%
  • G6802

    Granisetron Hydrochloride

    5-HT3 antagonist.

    ≥98%
  • T6932

    Triflumizole

    Imidazole; PPARγ agonist, RORγ inverse agonis...

    ≥95%
  • K0133

    Kainic Acid

    Excitatory amino acid found in seaweed; AMPA an...

    ≥98%
  • F4781

    Fludarabine

    Nucleoside (adenosine) analog; DNA chain termin...

    ≥98%
  • A5334

    Anisodamine

    Tropane alkaloid found in Solanaceae plants; α...

    ≥97%
  • A7868

    Atropine

    Tropane alkaloid found in plants in the Solanac...

    ≥98%
  • R8122

    Rufloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • I5210

    INCB018424

    JAK1/2 inhibitor.

    ≥98%
  • S8009

    Substance P (7-11)

    Endogenous tachykinin peptide, involved in infl...

    ≥95%
  • C0263

    L-Carnitine Hydrochloride

    Endogenous quaternary ammonium, required for fa...

    ≥98%
  • N8662

    NVP-BGJ398

    FGFR inhibitor.

    ≥98%
  • L589921

    Loxapine Succinate

    D2 and D4 dopamine receptor inhibitor.

    ≥99%
  • D3232

    3,3′-Diindolylmethane

    Indole found in cruciferous vegetables; AhR ago...

    ≥98%
  • S6000

    Sparfloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • D0263

    Dapoxetine Hydrochloride

    SERT inhibitor, potential voltage-gated K+ chan...

    ≥99%
  • S1853

    Senegenin

    Found in Polygata tennifolia.

    ≥98%
  • C9677

    Cyclocytidine Hydrochloride

    Pyrimidine nucleoside analog; DNA synthesis inh...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only