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Mebendazole

Mebendazole

Product ID M1605
Cas No. 31431-39-7
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $63.10 In stock
25 g $88.20 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
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  • Downloads
  • References
  • Custom Order

Description

Mebendazole is a benzimidazole anti-parasitic/anti-helminthic compound that also exhibits anticancer chemotherapeutic activity. Mebendazole inhibits microtubule polymerization in parasitic worms. In melanoma cells, mebendazole decreases levels of Bcl-2 and induces apoptosis, suppressing cell growth. This compound also decreases Bcl-2 and XIAP levels in vivo, suppressing growth of melanoma xenografts.

Product Info

Cas No.

31431-39-7

Purity

≥98%

Formula

C16H13N3O3

Formula Wt.

295.29

Chemical Name

(5-Benzoyl-1H-benzimidazole-2-yl)carbamic acid methyl ester

IUPAC Name

methyl N-(6-benzoyl-1H-benzimidazol-2-yl)carbamate

Synonym

Mebendazol, Lomper, Noverme, Pantelmin

Melting Point

288.5°C

Solubility

Soluble in formic acid. Practically insoluble in water, ethanol, ether and chloroform.

Appearance

Off white or yellowish powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

M1605 MSDS PDF

Info Sheet

M1605 Info Sheet PDF

References

Doudican NA, Byron SA, Pollock PM, et al. XIAP downregulation accompanies mebendazole growth inhibition in melanoma xenografts. Anticancer Drugs. 2013 Feb;24(2):181-8. PMID: 23059386.

Doudican N, Rodriguez A, Osman I, et al. Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. Mol Cancer Res. 2008 Aug;6(8):1308-15. PMID: 18667591.

El-On J. Benzimidazole treatment of cystic echinococcosis. Acta Trop. 2003 Feb;85(2):243-52. PMID: 12606103.

Custom Order

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