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Meropenem Trihydrate

Meropenem Trihydrate

Product ID M1769
Cas No. 119478-56-7
Purity ≥98%
Product Unit SizeCostQuantityStock
10 mg $81.70 In stock
50 mg $337.10 In stock
100 mg $408.30 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Meropenem is a β-lactam antibiotic that belongs to the family of carbapenems, active against all bacteria, with the most significant antibacterial activity against gram-negative species. Meropenem is somewhat resistant to degradation by β-lactamases and is used to treat bacterial meningitis, skin infections, and febrile neutropenia. This compound inhibits bacterial cell wall synthesis by binding penicillin-binding proteins 2 and 3 (PBP2/3), preventing formation of peptidoglycan.

Product Info

Cas No.

119478-56-7

Purity

≥98%

Formula

C17H25N3O5S • 3H2O

Formula Wt.

437.51

Chemical Name

(4R,5S,6S)-3-[(3S, 5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1- hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;trihydrate

IUPAC Name

(4R,5S,6S)-3-[(3S, 5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1- hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;trihydrate

Synonym

Merrem I.V.

Appearance

White to slightly yellow powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

M1769 MSDS PDF

Info Sheet

M1769 Info Sheet PDF

References

Mallick M, Odedra D, Vidyarthi AS, et al. Meropenem: a potent drug against superbug as unveiled through bioinformatics approaches. Int J Bioinform Res Appl. 2013;9(2):109-20. PMID: 23467058.

Pernot L, Frénois F, Rybkine T, et al. Crystal structures of the class D beta-lactamase OXA-13 in the native form and in complex with meropenem. J Mol Biol. 2001 Jul 20;310(4):859-74. PMID: 11453693.

Sumita Y, Fukasawa M. Potent activity of meropenem against Escherichia coli arising from its simultaneous binding to penicillin-binding proteins 2 and 3. J Antimicrob Chemother. 1995 Jul;36(1):53-64. PMID: 8537284.

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