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Mivacurium

Mivacurium

Product ID M3584
Cas No. 106861-44-3
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $135.20 In stock
100 mg $422.50 In stock
500 mg $1,086.00 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Mivacurium is a non-depolarizing, reversible neuromuscular junction blocker. Mivacurium acts as an anesthetic, inhibiting pre-synaptic nicotinic acetylcholine receptors (nAChRs) in neurons and muscle. Mivacurium exhibits a rapid onset and short duration of action. This compound also displays anti-fibrillatory/anti-arrhythmic activity, as its inhibition of signaling in the parasympathetic nervous system prevents atrial fibrillation in animal models.

Product Info

Cas No.

106861-44-3

Purity

≥98%

Formula

C58H80N2O14Cl2

Formula Wt.

1100.18

IUPAC Name

bis[3-[(1R)-6,7-dimethoxy-2-methyl-1-[(3,4,5-trimethoxyphenyl)methyl]-3, 4-dihydro-1H-isoquinolin-2-ium-2-yl]propyl] (E)-oct-4-enedioate;dichloride

Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

M3584 MSDS PDF

Info Sheet

M3584 Info Sheet PDF

References

Patterson E, Lu Z, Lin J, et al. Antifibrillatory properties of mivacurium in a canine model of atrial fibrillation. J Cardiovasc Pharmacol. 2008 Mar;51(3):293-303. PMID: 18356695.

Jonsson M, Gurley D, Dabrowski M, et al. Distinct pharmacologic properties of neuromuscular blocking agents on human neuronal nicotinic acetylcholine receptors: a possible explanation for the train-of-four fade. Anesthesiology. 2006 Sep;105(3):521-33. PMID: 16931985.

Feldman SA, Wu X, England A. Rate of 'onset' and 'offset' of four non-depolarising neuromuscular blocking drugs. Anaesthesia. 1995 Jun;50(6):510-3. PMID: 7618664.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
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