Description
MK-3697 is a selective orexin 2 receptor antagonist.
Product Unit Size | Cost | Quantity | Stock |
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MK-3697 is a selective orexin 2 receptor antagonist.
Cas No. | 1224846-01-8 |
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Purity | ≥98% |
Formula | C23H21N5O3S |
Formula Wt. | 447.5 |
Chemical Name | N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-(1,3-thiazol-2-yl)pyridine-4-carboxamide |
IUPAC Name | N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-(1,3-thiazol-2-yl)pyridine-4-carboxamide |
Synonym | MK3697; M8238285OA; (2,3'-Bipyridine)-4-carboxamide, N-((5,6-dimethoxy-2-pyridinyl)methyl)-5'-methyl-5-(2-thiazolyl)- |
Solubility | Insoluble in water. DMSO (>20 mg/mL). |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet |
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Roecker AJ, Reger TS, Mattern MC. et.al. Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia. Bioorg Med Chem Lett. (2014) 24:4884-90. PMID: 25248679 DOI: 10.1016/j.bmcl.2014.08.041.
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