Description
MK-3697 is a selective orexin 2 receptor antagonist.
| Product Unit Size | Cost | Quantity | Stock |
|---|
MK-3697 is a selective orexin 2 receptor antagonist.
| Cas No. | 1224846-01-8 |
|---|---|
| Purity | ≥98% |
| Formula | C23H21N5O3S |
| Formula Wt. | 447.5 |
| Chemical Name | N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-(1,3-thiazol-2-yl)pyridine-4-carboxamide |
| IUPAC Name | N-[(5,6-dimethoxypyridin-2-yl)methyl]-2-(5-methylpyridin-3-yl)-5-(1,3-thiazol-2-yl)pyridine-4-carboxamide |
| Synonym | MK3697; M8238285OA; (2,3'-Bipyridine)-4-carboxamide, N-((5,6-dimethoxy-2-pyridinyl)methyl)-5'-methyl-5-(2-thiazolyl)- |
| Solubility | Insoluble in water. DMSO (>20 mg/mL). |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet |
|---|
Roecker AJ, Reger TS, Mattern MC. et.al. Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia. Bioorg Med Chem Lett. (2014) 24:4884-90. PMID: 25248679 DOI: 10.1016/j.bmcl.2014.08.041.
Polyether Ca2+ ionophore.
Taxoid that disrupts the microtubular network i...
AurKA/B inhibitor.
Endogenous peptide hormone, involved in secreti...
Histamine H1-antagonist
Nitrofuran derivative.
Thiazide diuretic; NCCT inhibitor, carbonic anh...
Nitroimidazole; DNA synthesis inhibitor.
CysLT1 antagonist.
Flavanone found in species of Citrus. Naringen...
Peptide, substance P analog; NK agonist.
Statin; HMG-CoA reductase inhibitor, potential ...
Flavonoid glycoside found in fruit, asparagus, ...
Phenothiazine; D1/2 and α1-adrenergic antagoni...
Staurosporine derivative; PKC and FLT3 inhibito...
Rifamycin derivative, induces pore formation in...
Phytochemical from Nigella sativa.
Laminin-derived hexapeptide.
Protein translation inhibitor.
Iron chelator.