Description
MS346 is an inhibitor of bromodomain BRD4. This compound displays anti-inflammatory activity, decreasing the production of NO and pro-inflammatory cytokines in macrophages.
MS346 is an inhibitor of bromodomain BRD4. This compound displays anti-inflammatory activity, decreasing the production of NO and pro-inflammatory cytokines in macrophages.
| Cas No. | 1395084-25-9 |
|---|---|
| Purity | ≥99% |
| Formula | C18H17N5O3S |
| Formula Wt. | 383.43 |
| IUPAC Name | 4-[(E)-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-(2-pyridinyl)benzenesulfonamide |
| Solubility | 100mM in DMSO |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | |
|---|---|
| Info Sheet |
Zhang G, Plotnikov AN, Rusinova E, et al. Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J Med Chem. 2013 Nov 27;56(22):9251-64. PMID: 24144283.
DNA alkylator.
ITC, erysolin analog.
Benzyl taxol analog; potential microtubule depo...
Glycopeptide, vancomycin analog; peptidoglycan ...
Aminoglycoside; protein translation inhibitor, ...
Non-selective HDAC inhibitor.
Purine nucleoside analog; DNA chain terminator....
CB1 agonist, TRPV1 agonist.
Inhibitor of FAK and ALK.
Macrolide antibiotic; peptidyl transferase inhi...
Fluoroquinolone, optically active isomer of ofl...
Tetracycline; protein translation inhibitor, po...
ALK inhibitor.
Peptide, used to deliver conjugated drugs to ce...
Mixture of pyrantel, a thiophene, and pamoic ac...
Thiamine, coccidiostat; thiamine transporter in...
Neuropeptide found in crustaceans and insects.<...
Smac mimetic; IAP inhibitor.
CB2 receptor antagonist.
GSK3 and AChE inhibitor, potential σ1 agonist....