LKT Labs

Biochemicals for Life Science Research

MS436

MS436

Product ID M7200
Cas No. 1395084-25-9
Purity ≥99%
Product Unit SizeCostQuantityStock
1 mg $92.00 In stock
5 mg $179.00 In stock
25 mg $509.00 In stock
100 mg $1,048.00 In stock
Bulk Quote

Quicklinks

Description

MS346 is an inhibitor of bromodomain BRD4. This compound displays anti-inflammatory activity, decreasing the production of NO and pro-inflammatory cytokines in macrophages.

Product Info

Cas No.

1395084-25-9
Purity

≥99%
Formula

C18H17N5O3S
Formula Wt.

383.43
IUPAC Name

4-[(E)-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-(2-pyridinyl)benzenesulfonamide
Solubility

100mM in DMSO

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

M7200 MSDS PDF
Info Sheet

M7200 Info Sheet PDF

References

Zhang G, Plotnikov AN, Rusinova E, et al. Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J Med Chem. 2013 Nov 27;56(22):9251-64. PMID: 24144283.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • B3210

    R-Bicalutamide

    AR antagonist.

    ≥98%
  • A7460

    Asparaginase

    Catalyzes hydrolysis of asparagine.

    ≥98%
  • I2056

    Ifosfamide

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • T1676

    L-Tetrahydropalmatine

    Alkaloid found in Corydalis and Stephania; D1/2...

    ≥98%
  • A4000

    AK-1

    SIRT2 inhibitor.

    ≥99%
  • M5794

    Moxifloxacin Hydrochloride

    Fluoroquinolone; topoisomerase IV, topoisomeras...

    ≥98%
  • K6276

    (E)-KPT-330

    CRM1-selective inhibitor of nuclear export.

    ≥99%
  • N1744

    Nelarabine

    Nucleoside (guanosine) analog; DNA chain termin...

    ≥98%
  • C8070

    Curcumin, high purity

    Active compound found in turmeric; MST1 activat...

    ≥98%
  • C3208

    Ciclopirox Olamine

    Hydroxypyridone, metal ion chelator; mTOR inhib...

    ≥98%
  • A5032

    D,L-Aminoglutethimide

    Aromatase inhibitor.

    ≥98%
  • D3352

    Dinaciclib

    BRD binding agent, CDK1/2/5/9 inhibitor.

    ≥99%
  • C691325

    Cridanimod

    STING agonist

    ≥99%
  • C3210

    Ciglitazone

    Thiazolidinedione; PPARγ agonist.

    ≥98%
  • U6957

    Urotensin I

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • I7757

    Itopride Hydrochloride

    AChE inhibitor, D2 antagonist.

    ≥98%
  • X4402

    XL-147

    Dual inhibitor of PI3K and mTOR.

    ≥98%
  • A5315

    Deoxyandrographolide

    Labdane diterpene found in Andrographolis; cNOS...

    ≥98%
  • H9814

    25-Hydroxyvitamin D2

    Vitamin D2, ergocalciferol metabolite; VDR agon...

    ≥98%
  • C4559

    Clomiphene Citrate

    Used for in vitro fertilization; FIASMA, SERM.<...

    ≥98%