• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Naftopidil

Naftopidil

Product ID N0123
Cas No. 57149-07-2
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $126.50 In stock
100 mg $408.50 In stock
500 mg $1,080.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Naftopidil is an inhibitor of α1-adrenergic receptors that is clinically used to improve lower urinary tract symptoms in subjects with benign prostatic hyperplasia (BPH). In clinical trials, naftopidil improves nocturnal polyuria. Naftopidil improves bladder capacity through both its effect on adrenergic signaling as well as inhibition of c-fiber afferent nerves. Additionally, this compound inhibits collagen-induced Ca2+ mobilization and platelet aggregation in vitro, exhibiting potential anti-platelet benefit.

Product Info

Cas No.

57149-07-2

Purity

≥98%

Formula

C24H28N2O3

Formula Wt.

392.49

IUPAC Name

1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-naphthalen-1-yloxypropan-2-ol

Melting Point

209.0 - 212.0

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N0123 MSDS PDF

Info Sheet

N0123 Info Sheet PDF

References

Castiglione F, Benigni F, Briganti A, et al. Naftopidil for the treatment of benign prostate hyperplasia: a systematic review. Curr Med Res Opin. 2013 Dec 18. [Epub ahead of print]. PMID: 24188134.

Yokoyama O, Aoki Y, Tsujimura A, et al. α(1)-adrenoceptor blocker naftopidil improves sleep disturbance with reduction in nocturnal urine volume. World J Urol. 2011 Apr;29(2):233-8. PMID: 20387069.

Yokoyama O, Yusup A, Oyama N, et al. Improvement of bladder storage function by alpha1-blocker depends on the suppression of C-fiber afferent activity in rats. Neurourol Urodyn. 2006;25(5):461-7. PMID: 16673377.

Alarayyed NA, Cooper MB, Prichard BN, et al. In vitro adrenaline and collagen-induced mobilization of platelet calcium and its inhibition by naftopidil, doxazosin and nifedipine. Br J Clin Pharmacol. 1997 Apr;43(4):415-20. PMID: 9146854.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A5287

    Angiotensinogen (1-14), human

    Peptide fragment, renin substrate, precursor to...

    ≥95%
  • F6803

    FRAX486

    PAK inhibitor.Smo inhibitor.

    ≥98%
  • T5609

    β-Tocotrienol

    Antioxidant, vitamin E derivative found in vege...

    ≥98%
  • P7023

    Pregnenolone

    Endogenous precursor to all steroid hormones; T...

    ≥98%
  • S0225

    SAG Dihydrochloride

    Smoothened agonist.

    ≥98%
  • R0105

    Rabeprazole Sodium

    H+/K+ ATPase and Scpc phosphatase inhibitor.

    ≥98%
  • C0275

    Castanospermine

    O-GlcNAcase inhibitor.

    ≥98%
  • I4800

    Imatinib free base

    Inhibitor of Abl, c-Kit, and PDGFR.

    ≥99%
  • I458579

    Iloprost

    Prostacyclin analog

    ≥98%
  • I5208

    INCB-28060

    c-MET inhibitor.

    ≥98%
  • R5774

    Roscovitine

    CDK inhibitor, L-type Ca2+ channel blocker.

    ≥98%
  • P2100

    PF-06447475

    LRRK2 inhibitor.

    ≥98%
  • L8278

    Luteinizing Hormone Releasing Hormone, salmon

    Endogenous peptide hormone, involved in secreti...

    ≥95%
  • C2956

    Cholecalciferol

    Endogenous vitamin D prodrug.

    ≥98%
  • B6800

    Bradykinin Triacetate

    Natriuretic, vasodilatory peptide; B1/2 agonist...

    ≥95%
  • N1976

    Netilmicin Sulfate

    Aminoglycoside; protein translation inhibitor.<...

    ≥98%
  • M1579

    Methazolamide

    Carbonic anhydrase inhibitor.

    ≥98%
  • C9673

    Cysteamine Hydrochloride

    Aminothiol, CoA component; ulcer inducer.

    ≥99%
  • A7669

    A-type Natriuretic Peptide (1-28), rat

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥95%
  • O1078

    Octreotide Acetate

    Somatostatin analog, peptide; somatostatin agon...

    ≥95%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only