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Nizatidine

Product ID N3496
Cas No. 76963-41-2
Purity ≥98%
Product Unit SizeCostQuantityStock
5 g $64.90 In stock
10 g $111.30 In stock
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Nizatidine is an inverse agonist at histamine H2 receptors that exhibits antacid and immunostimulatory activities. Nizatidine shortens gastric emptying time in clinical settings. Additionally, this compound stimulates maturation of dendritic cells and displays potential benefit as an immunization adjuvant, boosting vaccine immune response.

Product Info

Cas No.

76963-41-2

Purity

≥98%

Formula

C12H21N5O2S2

Formula Wt.

331.46

Chemical Name

N-(2-(((2-((Dimethylamino)methyl)-4- thiazolyl)methyl)thio)ethyl)-N'-methyl-2-nitro- 1,1-ethenediamine

IUPAC Name

(E)-1-N'-[2-[[2-[(dimethylamino)methyl]-1, 3-thiazol-4-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1, 1-diamine

Synonym

Calmaxid, Cronizat, Distaxid, Gastrax, Naxidine, Nizax, Nizaxid, Tazac, Zanizal.

Melting Point

130-132°C

Solubility

Soluble in chloroform (>100mg/mL), methanol (50-100mg/mL), or water (10-33mg/mL).

Appearance

Almost White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

N3496 MSDS PDF

Info Sheet

N3496 Info Sheet PDF

References

Doi H, Sakakibara R, Sato M, et al. Nizatidine ameliorates gastroparesis in Parkinson's disease: a pilot study. Mov Disord. 2014 Apr;29(4):562-6. PMID: 24375669.

Wang S, Wu B, Xue J, et al. Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge. Hum Vaccin Immunother. 2014 Feb 1;10(2):461-8. PMID: 24253609.

Kurt A, Altun A, Bağcivan I, et al. Effects of proton pump inhibitors and h(2) receptor antagonists on the ileum motility. Gastroenterol Res Pract. 2011;2011:218342. PMID: 22216022.

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