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Ochratoxin B is the non-chlorinated analogue of the extensively studied mycotoxin, Ochratoxin A. It is a secondary metabolite of Aspergillus ochraceus. Its lower toxicity than the chlorinated analog, ochratoxin A, appears to be the result of its rapid metabolism and elimination.
| Cas No. | 4825-86-9 |
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| Purity | ≥99% |
| Formula | C20H19NO6 |
| Formula Wt. | 369.37 |
| Chemical Name | (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoic acid |
| IUPAC Name | (2S)-2-[[(3R)-8-hydroxy-3-methyl-1-oxo-3,4-dihydroisochromene-7-carbonyl]amino]-3-phenylpropanoic acid |
| Synonym | UNII-ECJ5WS94N2; CCRIS 5094; HSDB 3438; BRN 1300160 |
| Melting Point | 221°C |
| Solubility | DMSO: Clear yellow solution at 10mg/ml |
| Appearance | White to pale yellow powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Peckham JC, Doupnik B Jr, Jones OH Jr. Acute toxicity of ochratoxins A and B in chicks. Appl Microbiol. 1971,1(3):492-4. PMID: 4928604
Størmer FC, Kolsaker P, Holm H, Rogstad S, Elling F. Metabolism of ochratoxin B and its possible effects upon the metabolism and toxicity of ochratoxin A in rats. Appl Environ Microbiol. 1985 May;49(5):1108-12. PMID: 4004232.
Mally A , Keim-Heusler H, Amberg A, et al. Biotransformation and nephrotoxicity of ochratoxin B in rats. Toxicol Appl Pharmacol. 2005; 206(1):43-53. PMID: 15963343.