Oleuropein

Name: Oleuropein
SKU: O446185
Availability: InStock

Product ID O446185

Cas No. 32619-42-4

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Oleuropein is a bioactive compound found in all parts of the olive tree. Oleuropein has been shown to reduce intracellular ROS generation, inhibit apoptosis, stabilize mitochondrial membrane potential, modulate apoptotic proteins, and increase phosphorylation of Akt and ERK1/2 in neonatal rat cardiomyocytes subjected to simulation of ischemia/reperfusion. Additionally, oleuropein has been found to decrease COX-2 expression, suppress IL-17 in mucosa and supernatant, and attenuate inflammatory damage in colonic biopsy cultures or samples of ulcerative colitis. Furthermore, oleuropein was found to significantly increase radiosensitivity of nasopharyngeal carcinoma cells by reducing expression of HIF1alpha, in addition to altering expressions of miRNAs and genes.

Product Info

Cas No.	32619-42-4
Purity	≥98%
Formula	C₂₅H₃₂O₁₃
Formula Wt.	540.52
Chemical Name	(2S,3E,4S)-3-ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetic acid, 2-(3,4-dihydroxyphenyl)ethyl ester
IUPAC Name	methyl (4S,5E,6S)-4-[2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl]-5-ethylidene-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4H-pyran-3-carboxylate
Synonym	Oleoeuropein
Solubility	DMSO:100 mg/mL (185.01 mM) Water:100 mg/mL warmed (185.01 mM) Ethanol:100 mg/mL warmed (185.01 mM)
Appearance	White to off white powder

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	O446185 MSDS PDF
Info Sheet	O446185 Info Sheet PDF

References

Garcia-Molina G, Peters E, Palmeri R, et al. Enzymatic synthesis of hydroxytyrosol from oleuropein for valorization of an agricultural waste. Bioengineered. 2024 Dec;15(1):2396647. PMID: 39235136.

Zhao Q, Bai Y, Li C, et al. Oleuropein protects cardiomyocyte against apoptosis via activating the reperfusion injury salvage kinase pathway in vitro. Evid Based Complement Alternat Med. 2017. 2017:2109018. PMID: 28491103.

Larussa T, Oliverio M, Suraci E, et al. Oleuropein decreases cyclooxygenase-2 and interleukin-17 expression and attenuates inflammatory damage in colonic samples from ulcerative colitis patients. Nutrients. 2017 Apr 15;9(4).pii:E391. PMID: 28420140.

Xu T, Xiao D. Oleuropein enhances radiation sensitivity of nasopharyngeal carcinoma by downregulating PDRG1 through HIF1alpha-repressed microRNA-519d. J Exp Clin cancer Res. 2017 Jan 5;36(1):3. PMID: 28057028.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Email
This field is for validation purposes and should be left unchanged.

Oleuropein

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Auraptene

Flupirtine Maleate

Acetylsalicylic Acid

URB597

Cilostazol

Nefiracetam

AMG-208

Atenolol

R-Bicalutamide

3-Formylrifamycin

CKS-17

Etoricoxib

Nifedipine

Aflatoxin B2

Pituitary Adenylate Cyclase-activating Polypeptide (1-27), human, sheep, rat

Verapamil Hydrochloride

Hydrolyzed Fumonisin B1

Azelnidipine

Urapidil

Erucin

Footer