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Omeprazole Related Compound A

Omeprazole Related Compound A

Product ID O486180
Cas No. 88546-55-8
Purity ≥99%
Product Unit SizeCostQuantityStock
5 mg $128.60 In stock
25 mg $457.90 In stock
100 mg $1,380.90 In stock
Bulk Quote

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  • Description
  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
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Description

Omeprazole related compound A (omeprazole sulfone) is a metabolite of omeprazole found in individuals who are taking the drug. The isozyme, CYP3A4, of the P450 drug metabolizing enzyme appears to be responsible for the oxidation of the sulfoxide of omeprazole in a stereoselective manner to its sulfone .

Product Info

Cas No.

88546-55-8

Purity

≥99%

Formula

C17H19N3O4S

Formula Wt.

361.42

Chemical Name

5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfonyl)-1H-benzo[d]imidazole

IUPAC Name

6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfonyl]-1H-benzimidazole

Synonym

Omeprazole sulfone; Omeprazole sulphone; omeprazole impurity D; Omeprazole metabolite Omeprazole sulfone; UNII-76X040Z74O   

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

O486180 MSDS PDF

Info Sheet

O486180 Info Sheet PDF

References

Mihaly GW, Prichard PJ, Smallwood RA, et al. Simultaneous high-performance liquid chromatographic analysis of omeprazole and its sulphone and sulphide metabolites in human plasma and urine. J Chromatogr. 1983;278(2):311-9. PMID: 6668312.

Abelö A1, Andersson TB, Antonsson M, et al. Stereoselective metabolism of omeprazole by human cytochrome P450 enzymes. Drug Metab Dispos. 2000;28(8):966-72. PMID: 10901708

Custom Order

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