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Ovalbumin (257-264) is an antigenic peptide fragment of ovalbumin that contains a CD8+ cytotoxic T-cell (CTL)-specific epitope with the sequence ‘SIINFEKL.’ This fragment is administered in vaccines to stimulate a Th1 immune response.
| Purity | ≥98% |
|---|---|
| Formula | C45H74N10O13 |
| Formula Wt. | 963.2 |
| Synonym | albumin, OVA (257-264) |
| Solubility | Moderately soluble in water. |
| Appearance | White to off-white powder |
| Store Temp | -20°C |
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| Ship Temp | Ambient |
| MSDS | |
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| Info Sheet |
Cheng WK, Wee K, Kollmann TR, et al. Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes. Clin Vaccine Immunol. 2014 Mar;21(3):329-39. PMID: 24391136.
Xie Y, Wang L, Freywald A, et al. A novel T cell-based vaccine capable of stimulating long-term functional CTL memory against B16 melanoma via CD40L signaling. Cell Mol Immunol. 2013 Jan;10(1):72-7. PMID: 23042534.
Denton AE, Wesselingh R, Gras S, et al. Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses. J Immunol. 2011 Dec 1;187(11):5733-44. PMID: 22039305.
Jameson SC, Bevan MJ. Dissection of major histocompatibility complex (MHC) and T cell receptor contact residues in a Kb-restricted ovalbumin peptide and an assessment of the predictive power of MHC-binding motifs. Eur J Immunol. 1992 Oct;22(10):2663-7. PMID: 1396971.