LKT Labs

Biochemicals for Life Science Research

Pancreastatin, porcine

Pancreastatin, porcine

Product ID P0352
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $761.30 Please Inquire
1 mg $1,260.00 Please Inquire
2.5 mg $2,100.00 Please Inquire
Bulk Quote

Quicklinks

Description

Pancreastatin is an endogenous peptide derived from chromogranin-A that regulates insulin action, inhibiting insulin secretion and increasing glucagon secretion. Pancreastatin binds and inhibits GRP78, decreasing insulin-stimulated glucose uptake and expression of G6Pase. This peptide displays pro-diabetic activity and induces glycogenolysis and lipolysis. Pancreastatin is also used as a biomarker to detect neuroendocrine tumors and shows some correlation with diabetes and hypertension.

Product Info

Purity

≥98%
Formula

C214H330N68O76S
Formula Wt.

5103.45
Synonym

PST
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

P0352 Info Sheet PDF

References

Biswas N, Friese RS, Gayen JR, et al. Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism. PLoS One. 2014 Jan 20;9(1):e84132. PMID: 24465394.

Rustagi S, Warner RR, Divino CM. Serum pancreastatin: the next predictive neuroendocrine tumor marker. J Surg Oncol. 2013 Aug;108(2):126-8. PMID: 23775817.

Sánchez-Margalet V, González-Yanes C, Najib S, et al. Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin. Regul Pept. 2010 Apr 9;161(1-3):8-14. PMID: 20184923.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • C0221

    Caffeine

    Xanthine alkaloid found in coffee, tea, and oth...

    ≥98%
  • B6806

    Bradykinin (2-9)

    Natriuretic, vasodilatory peptide fragment; B1/...

    ≥95%
  • P7000

    PR-619

    Deubiquitinating enzyme inhibitor.

    ≥98%
  • A5314

    Dehydroandrographolide

    Labdane diterpene found in Andrographis.

    ≥98%
  • R0249

    Ramipril

    ACE inhibitor.

    ≥98%
  • A5162

    Amprolium Hydrochloride

    Thiamine, coccidiostat; thiamine transporter in...

    ≥97%
  • L0400

    LB-100

    PP2A inhibitor.

    ≥98%
  • R0348

    Ramelteon

    Melatonin analog; MT1/2 agonist.

    ≥99%
  • V5886

    Voriconazole

    Triazole; 14α demethylase inhibitor.

    ≥98%
  • C2969

    Chromomycin A3

    Anthraquinone, Mg2+/Zn2+ chelator; bacterial DN...

    ≥97%
  • P2845

    Phleomycin

    Glycopeptide, metal ion chelator, induces DNA s...

    ≥97%
  • C1718

    Cepharanthine, 95%

    Alkaloid found in Stephania.

    ≥95%
  • C9615

    Cyclosporin B

    Cyclic peptide; calcineurin inhibitor.

    ≥95%
  • C8112

    CUDC-907

    PI3K and HDAC inhibitor.

    ≥98%
  • E7376

    Estradiol

    Endogenous steroid hormone, involved in regulat...

    ≥97%
  • L589940

    LOXO-101

    Inhibitor of tropomyosin kinase receptors TRKA,...

    ≥99%
  • G7340

    GSK-126

    EZH2 HMT inhibitor.

    ≥98%, ≥99%ee
  • C0374

    β-Casomorphin, human

    Peptide, casein fragment.

    ≥95%
  • C211324

    CFI-400945

    PLK4 inhibitor.

    ≥98%
  • S1604

    Secretin Acetate

    Endogenous peptide hormone, involved in feeding...

    ≥95%