LKT Labs

Biochemicals for Life Science Research

Pancreastatin, porcine

Pancreastatin, porcine

Product ID P0352
Cas No.
Purity ≥98%
Product Unit SizeCostQuantityStock
0.5 mg $761.00 Please Inquire
1 mg $1,260.00 Please Inquire
2.5 mg $2,100.00 Please Inquire
Bulk Quote

Quicklinks

Description

Pancreastatin is an endogenous peptide derived from chromogranin-A that regulates insulin action, inhibiting insulin secretion and increasing glucagon secretion. Pancreastatin binds and inhibits GRP78, decreasing insulin-stimulated glucose uptake and expression of G6Pase. This peptide displays pro-diabetic activity and induces glycogenolysis and lipolysis. Pancreastatin is also used as a biomarker to detect neuroendocrine tumors and shows some correlation with diabetes and hypertension.

Product Info

Purity

≥98%
Formula

C214H330N68O76S
Formula Wt.

5103.45
Synonym

PST
Solubility

Soluble in water.

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

Info Sheet

P0352 Info Sheet PDF

References

Biswas N, Friese RS, Gayen JR, et al. Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism. PLoS One. 2014 Jan 20;9(1):e84132. PMID: 24465394.

Rustagi S, Warner RR, Divino CM. Serum pancreastatin: the next predictive neuroendocrine tumor marker. J Surg Oncol. 2013 Aug;108(2):126-8. PMID: 23775817.

Sánchez-Margalet V, González-Yanes C, Najib S, et al. Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin. Regul Pept. 2010 Apr 9;161(1-3):8-14. PMID: 20184923.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • O610292

    Ophiobolin B

    Naturally occurring sesteterpenoid.

    ≥98%
  • C0016

    Caerulomycin A

    Bipyridamine toxin.

    ≥96%
  • D3575

    2,5-Di-tert-butyl-4-hydroxyanisole

    BHA derivative; potential Ca2+ ATPase inhibitor...

    ≥98%
  • L1616

    LEE-011

    CDK4/6 inhibitor.

    ≥98%
  • D5994

    Doxepin Hydrochloride

    FIASMA, 5-HT1/2, M1-5 mAChR, α1-adrenergic, hi...

    ≥98%
  • M0009

    Macitentan

    ET-A/B antagonist.

    ≥99%
  • S1609

    Securinine

    Alkaloid found in Securinega; potential GABA-A ...

    ≥98%
  • A0916

    Acepromazine Maleate

    Phenothiazine derivative; D1/2 and 5-HT1A/2A an...

    ≥99%
  • T291321

    Thiamine Mononitrate

    Vitamin B1

    ≥98%
  • C2960

    Chondroitin Sulfate, cow

    Polyanionic sulfated glycosaminoglycan, encogen...

    ≥90%
  • D3353

    Diminazene Aceturate

    Diamidine; ACE2 activator, DNA polymerase inhib...

    ≥98%
  • N8760

    NVP-TAE684

    ALK, c-Fes, LRRK2 inhibitor.

    ≥98%
  • S0225

    SAG Dihydrochloride

    Smoothened agonist.

    ≥98%
  • A744789

    ASTX660

    Antitumor

    ≥98%
  • H9816

    2-Hydroxyestradiol

    Estradiol metabolite.

    ≥99%
  • L960002

    LY-294002 Hydrochloride

    Inhibitor of PI3K.

    ≥98%
  • B0110

    Baclofen

    GABA derivative; GABA-B agonist.

    ≥98%
  • D1874

    Desvenlafaxine Succinate Hydrate

    Venlafaxine metabolite; SERT and NET inhibitor....

    ≥99%
  • G4781

    Glucoraphanin Potassium

    Glucosinolate found in cruciferous vegetables.<...

    ≥98%
  • S3568

    Siramesine

    σ2 agonist.

    ≥98%