LKT Labs

Biochemicals for Life Science Research

Phytanic Acid

Phytanic Acid

Product ID P3198
Cas No. 14721-66-5
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $236.40 Please Inquire
25 mg $756.20 In stock
Bulk Quote

Quicklinks

Description

Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to regulate glucose metabolism. Phytanic acid also plays a role in disorders of peroxisomal metabolism such as Refsum disease. This compound induces apoptosis by uncoupling oxidative phosphorylation, stimulating ROS generation, and activating the free fatty acid receptor GPR40 to alter intracellular Ca2+ levels.

Product Info

Cas No.

14721-66-5
Purity

≥97%
Formula

C20H40O2
Formula Wt.

312.53
IUPAC Name

3,7,11,15-tetramethylhexadecanoic acid
Synonym

3,7,11,15-Tetramethylhexadecanoic acid
Solubility

Soluble in water (< 0.1 mg/ml at 25° C), DMSO (~100 mg/ml), DMF (~100 mg/ml), and 0.15 M Tris-HCl (pH 8.5) solution (1 mg/ml)
Appearance

Liquid

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P3198 MSDS PDF
Info Sheet

P3198 Info Sheet PDF

References

Che BN, Oksbjerg N, Hellgren LI, et al. Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes. Lipids Health Dis. 2013 Feb 11;12:14. PMID: 23398851.

Busanello EN, Amaral AU, Tonin AM, et al. Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats. Cerebellum. 2013 Jun;12(3):362-9. PMID: 23081695.

Kruska N, Reiser G. Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. Neurobiol Dis. 2011 Aug;43(2):465-72. PMID: 21570468.

Schönfeld P, Kahlert S, Reiser G. A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes. Exp Gerontol. 2006 Jul;41(7):688-96. PMID: 16616447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • A491337

    9-Aminocamptothecin Hydrochloride

    Derivative of camptothecin.

    ≥98%
  • A7672

    Atropine Sulfate Monohydrate

    Tropane alkaloid found in Solanaceae plants; mA...

    ≥98%
  • E6783

    R-Equol

    Isoflavone, phytoestrogen found in soy

    ≥98%
  • G3552

    20S-Ginsenoside Rg3

    Triterpene saponin found in Panax; Kv7.1 K+ cha...

    ≥98%
  • A3212

    3′-Azido-3′-deoxythymidine

    Nucleoside (thymidine) analog; DNA chain termin...

    ≥98%
  • P7628

    Parathyroid Hormone-Related Protein (1-34), human/rat

    Endogenous peptide hormone, increases extracell...

    ≥95%
  • L9610

    Lycorine Hydrochloride

    Alkaloid found in plants in the Amaryllidaceae ...

    ≥98%
  • C1176

    CCT-128930

    Pyrrolopyrimidine; Akt inhibitor.

    ≥98%
  • P6801

    Pravastatin Sodium

    Statin; HMG-CoA reductase inhibitor.

    ≥98%
  • N4974

    NMS-E628

    ALK and Ros1 inhibitor, Trk antagonist.

    ≥98%
  • P8168

    Puromycin Dihydrochloride

    Protein synthesis inhibitor, DPP2 and metallope...

    ≥98%
  • P2815

    Phenylbutyrate Sodium

    HDAC inhibitor.

    ≥98%
  • C1621

    CEF4

    Peptide, vSrc-induced cytokine.

    ≥95%
  • C0248

    Calcineurin Substrate

    Peptide used to measure in vitro calcineurin ac...

    ≥96%
  • Z7477

    ZSTK474

    PI3K inhibitor.

    ≥98%
  • U6957

    Urotensin I

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • D1720

    Deferiprone

    Iron chelator.

    ≥99%
  • C3446

    Cilnidipine

    Dihydropyridine; L-type and N-type Ca2+ channel...

    ≥98%
  • C0274

    Caspofungin Diacetate

    Lipopeptide; 1,3-β-Glucan synthase inhibitor.<...

    ≥95%
  • G1658

    Gentamycin Sulfate

    Aminoglycoside; protein translation inhibitor.<...