LKT Labs

Biochemicals for Life Science Research

Phytanic Acid

Phytanic Acid

Product ID P3198
Cas No. 14721-66-5
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $236.40 Please Inquire
25 mg $756.20 In stock
Bulk Quote

Quicklinks

Description

Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to regulate glucose metabolism. Phytanic acid also plays a role in disorders of peroxisomal metabolism such as Refsum disease. This compound induces apoptosis by uncoupling oxidative phosphorylation, stimulating ROS generation, and activating the free fatty acid receptor GPR40 to alter intracellular Ca2+ levels.

Product Info

Cas No.

14721-66-5
Purity

≥97%
Formula

C20H40O2
Formula Wt.

312.53
IUPAC Name

3,7,11,15-tetramethylhexadecanoic acid
Synonym

3,7,11,15-Tetramethylhexadecanoic acid
Solubility

Soluble in water (< 0.1 mg/ml at 25° C), DMSO (~100 mg/ml), DMF (~100 mg/ml), and 0.15 M Tris-HCl (pH 8.5) solution (1 mg/ml)
Appearance

Liquid

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P3198 MSDS PDF
Info Sheet

P3198 Info Sheet PDF

References

Che BN, Oksbjerg N, Hellgren LI, et al. Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes. Lipids Health Dis. 2013 Feb 11;12:14. PMID: 23398851.

Busanello EN, Amaral AU, Tonin AM, et al. Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats. Cerebellum. 2013 Jun;12(3):362-9. PMID: 23081695.

Kruska N, Reiser G. Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. Neurobiol Dis. 2011 Aug;43(2):465-72. PMID: 21570468.

Schönfeld P, Kahlert S, Reiser G. A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes. Exp Gerontol. 2006 Jul;41(7):688-96. PMID: 16616447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • E7758

    Etomidate

    GABA-A agonist.

    ≥99%
  • N7209

    NSC-207895

    Benzofuroxan derivative; MDMX inhibitor.

    ≥98%
  • A4497

    Alyssin Sulfone

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • T8006

    Tubastatin A Hydrochloride

    HDAC6/10 inhibitor.

    ≥98%
  • N3496

    Nizatidine

    Histamine H2 inverse agonist.

    ≥98%
  • V7200

    VS-5584

    PI3K inhibitor.

    ≥98%
  • G3254

    10-Gingerol

    Phenol found in Zingiber; 5-HT3 antagonist.

    ≥99%
  • C000171

    C-171

    STING inhibitor

    ≥98%
  • G3553

    Ginsenoside Rb2

    Triterpene saponin found in species of Panax.

    ≥98%
  • E5575

    Entacapone

    COMT inhibitor.

    ≥98%
  • B1769

    Bergenin

    Trihydroxybenzoic acid glycoside found in Berge...

    ≥98%
  • J974440

    JZL184

    MAGL inhibitor.

    ≥98%
  • Z0146

    Z-Ala-Ala-Leu-pNA

    Proteinase subtrate.

    ≥95%
  • A4496

    Alyssin

    Naturally sourced ITC, sulfonyl analog of sulfo...

    ≥97%
  • G0182

    Gastrin Releasing Peptide, pig

    Endogenous bombesin-like peptide, involved in f...

    ≥98%
  • B0110

    Baclofen

    GABA derivative; GABA-B agonist.

    ≥98%
  • P327211

    Pifithrin-α Hydrobromide

    p53 inhibitor

    ≥98%
  • E7858

    Etoricoxib

    NSAID; COX-2 inhibitor.

    ≥99%
  • S0500

    SB-203580

    p38 MAPK inhibitor.

    ≥98%
  • J6400

    (+)-JQ-1

    Triazolothienodiazepine; BRD inhibitor.

    ≥99%