LKT Labs

Biochemicals for Life Science Research

Phytanic Acid

Phytanic Acid

Product ID P3198
Cas No. 14721-66-5
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $236.40 Please Inquire
25 mg $756.20 In stock
Bulk Quote

Quicklinks

Description

Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to regulate glucose metabolism. Phytanic acid also plays a role in disorders of peroxisomal metabolism such as Refsum disease. This compound induces apoptosis by uncoupling oxidative phosphorylation, stimulating ROS generation, and activating the free fatty acid receptor GPR40 to alter intracellular Ca2+ levels.

Product Info

Cas No.

14721-66-5
Purity

≥97%
Formula

C20H40O2
Formula Wt.

312.53
IUPAC Name

3,7,11,15-tetramethylhexadecanoic acid
Synonym

3,7,11,15-Tetramethylhexadecanoic acid
Solubility

Soluble in water (< 0.1 mg/ml at 25° C), DMSO (~100 mg/ml), DMF (~100 mg/ml), and 0.15 M Tris-HCl (pH 8.5) solution (1 mg/ml)
Appearance

Liquid

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P3198 MSDS PDF
Info Sheet

P3198 Info Sheet PDF

References

Che BN, Oksbjerg N, Hellgren LI, et al. Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes. Lipids Health Dis. 2013 Feb 11;12:14. PMID: 23398851.

Busanello EN, Amaral AU, Tonin AM, et al. Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats. Cerebellum. 2013 Jun;12(3):362-9. PMID: 23081695.

Kruska N, Reiser G. Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. Neurobiol Dis. 2011 Aug;43(2):465-72. PMID: 21570468.

Schönfeld P, Kahlert S, Reiser G. A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes. Exp Gerontol. 2006 Jul;41(7):688-96. PMID: 16616447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • M0126

    Magainin 2

    Antimicrobial peptide found in frogs, induces p...

    ≥95%
  • T9968

    Tyrphostin A25

    SK K+ channel blocker, EGFR inhibitor.

    ≥98%
  • S1872

    Sesamin

    Lignin found in Sesamin indicum;

    ≥98%
  • T0251

    Tamsulosin Hydrochloride

    α1-adrenergic antagonist.

    ≥98%
  • P0244

    Palbociclib Hydrochloride

    CDK4/6 inhibitor.

    ≥99%
  • L0108

    Lacidipine

    Calcium channel blocker.

    ≥98%
  • C3352

    Cinacalcet Hydrochloride

    Ca2+-sensing receptor agonist.

    ≥99%
  • S6247

    Splitomicin

    SIRT1/2 inhibitor.

    ≥98%
  • T3032

    Thienyldecyl Isothiocyanate

    Thienylbutyl ITC analog.

    ≥95%
  • C022682

    2-Carbomethoxy-3-thiophenesulfonyl Chloride

    Building block

    ≥98%
  • E0403

    Ebastine

    Histamine H1 antagonist.  
    ≥98%
  • A9435

    Axitinib

    VEGFR inhibitor.

    ≥98%
  • A040068

    AB-680

    CD73 inhibitor

    ≥98%
  • M3310

    Miconazole Nitrate

    Imidazole; 14-α demethylase inhibitor, potenti...

    ≥98%
  • D1777

    Desmopressin Acetate

    Synthetic peptide, vasopressin derivative; V2 a...

    ≥95%
  • O938567

    4-epi-6-Oxodocetaxel

    Docetaxel impurity

    ≥95%
  • I4659

    Iloperidone

    Benzisoxazole phenylethanone; D2 and 5-HT2A ant...

    ≥99%
  • M4452

    MLN2480

    Raf inhibitor.

    ≥98%
  • S164098

    Seco-rapamycin

    Rapamycin analog

    ≥73%
  • E9416

    Exendin-3

    Peptide, GLP-1 analog found in Heloderma; GLP-1...

    ≥95%