LKT Labs

Biochemicals for Life Science Research

Phytanic Acid

Phytanic Acid

Product ID P3198
Cas No. 14721-66-5
Purity ≥97%
Product Unit SizeCostQuantityStock
5 mg $236.40 Please Inquire
25 mg $756.20 In stock
Bulk Quote

Quicklinks

Description

Phytanic acid is a fatty acid metabolite of chlorophyll that acts as a ligand of retinoid X receptors (RXRs) and peroxisome proliferator-activated receptors (PPARs) and is known to regulate glucose metabolism. Phytanic acid also plays a role in disorders of peroxisomal metabolism such as Refsum disease. This compound induces apoptosis by uncoupling oxidative phosphorylation, stimulating ROS generation, and activating the free fatty acid receptor GPR40 to alter intracellular Ca2+ levels.

Product Info

Cas No.

14721-66-5
Purity

≥97%
Formula

C20H40O2
Formula Wt.

312.53
IUPAC Name

3,7,11,15-tetramethylhexadecanoic acid
Synonym

3,7,11,15-Tetramethylhexadecanoic acid
Solubility

Soluble in water (< 0.1 mg/ml at 25° C), DMSO (~100 mg/ml), DMF (~100 mg/ml), and 0.15 M Tris-HCl (pH 8.5) solution (1 mg/ml)
Appearance

Liquid

Shipping and Storage

Store Temp

-20°C
Ship Temp

Ambient

Downloads

MSDS

P3198 MSDS PDF
Info Sheet

P3198 Info Sheet PDF

References

Che BN, Oksbjerg N, Hellgren LI, et al. Phytanic acid stimulates glucose uptake in a model of skeletal muscles, the primary porcine myotubes. Lipids Health Dis. 2013 Feb 11;12:14. PMID: 23398851.

Busanello EN, Amaral AU, Tonin AM, et al. Disruption of mitochondrial homeostasis by phytanic acid in cerebellum of young rats. Cerebellum. 2013 Jun;12(3):362-9. PMID: 23081695.

Kruska N, Reiser G. Phytanic acid and pristanic acid, branched-chain fatty acids associated with Refsum disease and other inherited peroxisomal disorders, mediate intracellular Ca2+ signaling through activation of free fatty acid receptor GPR40. Neurobiol Dis. 2011 Aug;43(2):465-72. PMID: 21570468.

Schönfeld P, Kahlert S, Reiser G. A study of the cytotoxicity of branched-chain phytanic acid with mitochondria and rat brain astrocytes. Exp Gerontol. 2006 Jul;41(7):688-96. PMID: 16616447.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • I4659

    Iloperidone

    Benzisoxazole phenylethanone; D2 and 5-HT2A ant...

    ≥99%
  • P6857

    Protocatechuic Acid

    Polyphenol found in many plants and foods.

    ≥97%
  • T291321

    Thiamine Mononitrate

    Vitamin B1

    ≥98%
  • C2468

    β-Calcitonin Gene Related Peptide, human

    Endogenous calcitonin-family peptide, involved ...

    ≥98%
  • D3302

    Diaveridine Hydrochloride

    Coccidiostat; dihydrofolate reductase inhibitor...

    ≥98%
  • G124084

    GDC-0973

    MEK1 inhibitor.

    ≥99%
  • B1992

    Bexarotene

    RXR agonist.

    ≥98%
  • T6931

    Triclosan

    Diarylether; bacterial ENR binder, fatty acid s...

    ≥98%
  • S3353

    Sinomenine Hydrochloride

    Alkaloid found in Sinomenium; acid-sensing ion ...

    ≥98%
  • R5894

    Roxatidine Acetate Hydrochloride

    Histamine H2 antagonist.

    ≥98%
  • U451349

    Ulixertinib

    May induce apoptosis in lymphoma cell lines.

    ≥98%
  • D1624

    Deflazacort

    Oxazoline; glucocorticoid agonist.

    ≥98%
  • I5210

    INCB018424

    JAK1/2 inhibitor.

    ≥98%
  • T2833

    1-Thio-β-D-glucose Tetraacetate

    Imaging agent; Maillard reaction inhibitor.

    ≥98%
  • U6858

    Urocortin II, mouse

    Endogenous peptide, involved in stress signalin...

    ≥95%
  • T0393

    (+/-)-Taxifolin Hydrate

    Catechol-type flavonoid.

    ≥95%
  • L960008

    LY-3177833

    Cdc7 inhibitor.

    ≥99%
  • E6256

    Epothilone A

    Microtubule depolymerization inhibitor.

    ≥95%
  • P1955

    Pentagastrin

    Synthetic peptide, stimulates gastric acid secr...

    ≥95%
  • P4492

    PLX4720

    V600E B-Raf inhibitor.

    ≥98%