Description
PIK-293 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K. PIK-293 is the parent compound of PIK-294.
PIK-293
Product ID P3440
Cas No. 900185-01-5
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
|---|
Product Info
| Cas No. | 900185-01-5 |
|---|---|
| Purity | ≥98% |
| Formula | C22H19N7O |
| Formula Wt. | 397.43 |
| Chemical Name | 2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one |
| IUPAC Name | 2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one |
| Synonym | PIK-293, PIK293, PIK 293 |
| Solubility | DMSO 80 mg/mL (201.29 mM) Water Insoluble Ethanol Insoluble |
| Appearance | Pale Yellow Powder |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | |
|---|---|
| Info Sheet |
References
Hong J, Dicker B, Jayasinghe S, et al. Strong inhibition of neutrophil-sperm interaction in cattle by selective phosphatidylinositol 3-kinase inhibitors. Biol Reprod. 2017 Nov 1;97(5):671-687. PMID: 29036279.
Setti A, Kumar M, Babu K, et al. Potency and pharmacokinetics of broad spectrum and isoform-specific p110gamma and delta inhibitors in cancers. J Recept Signal Transduct Res. 2016;36(1):26-36. PMID: 26791581.
Martin K, Muessel M, Pullar C, et al. The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels. PLoS One. 2015 Feb 6;10(2):e0116250. PMID: 25659107.