Description
PIK-294 is an inhibitor of PI3K that is somewhat selective for p110δ PI3K and less sensitive to p110α PI3K.
PIK-294
Product ID P3441
Cas No. 900185-02-6
Purity ≥98%
| Product Unit Size | Cost | Quantity | Stock |
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Product Info
| Cas No. | 900185-02-6 |
|---|---|
| Purity | ≥98% |
| Formula | C28H23N7O2 |
| Formula Wt. | 489.53 |
| IUPAC Name | 2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one |
| Solubility | DMSO (98 mg/ml), insoluble in water |
| Appearance | White to off white powder |
Shipping and Storage
| Store Temp | -20°C |
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| Ship Temp | Ambient |
Downloads
| MSDS | |
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| Info Sheet |
References
Hong J, Dicker B, Jayasinghe S, et al. Strong inhibition of neutrophil-sperm interaction in cattle by selective phosphatidylinositol 3-kinase inhibitors. Biol Reprod. 2017 Nov 1;97(5):671-687. PMID: 29036279.
Setti A, Kumar M, Babu K, et al. Potency and pharmacokinetics of broad spectrum and isoform-specific p110gamma and delta inhibitors in cancers. J Recept Signal Transduct Res. 2016;36(1):26-36. PMID: 26791581.
Martin K, Muessel M, Pullar C, et al. The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels. PLoS One. 2015 Feb 6;10(2):e0116250. PMID: 25659107.