Prostaglandin E1

Name: Prostaglandin E1
SKU: P6956
Availability: InStock

Product ID P6956

Cas No. 745-65-3

Purity ≥98%

Product Unit Size	Cost	Quantity		Stock

Bulk Quote

Quicklinks

Description
Product Info
Shipping and Storage
Downloads
References

Description

Prostaglandin E1 (PGE1) is an endogenous prostaglandin synthesized from linolenic acid. PGE1 is clinically used for its vasodilatory activity as a treatment for erectile dysfunction. PGE1 also exhibits nephroprotective and pro-angiogenic activities. PGE1 decreases small intestine mucosa lesions in animal models of intestinal ischemia/reperfusion. PGE1 also improves renal function in subject with renal dysfunction or renal failure. Additionally, PGE1 enhances VEGF production in animal models of ischemia.

Product Info

Cas No.	745-65-3
Purity	≥98%
Formula	C₂₀H₃₄O₅
Formula Wt.	354.48
Chemical Name	(11a,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-enoic acid
IUPAC Name	7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
Synonym	Alprostadil, PGE1, Caverject, Muse, Prostandin, Prostin VR
Melting Point	115-116°C
Solubility	Soluble in ethanol (5mg/mL) or acetone (10mg/mL).
Appearance	White Needle Crystal

Shipping and Storage

Store Temp	-20°C
Ship Temp	Ambient

Downloads

MSDS	P6956 MSDS PDF
Info Sheet	P6956 Info Sheet PDF

References

Hanchanale V, Eardley I. Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. PMID: 24369066.

Brasileiro JL, Inoye CM, Aydos RD, et al. Ischemia and reperfusion of rat small intestine using pentoxyfilline and prostaglandin E1. Acta Cir Bras. 2013 Nov;28(11):767-73. PMID: 24316743.

Liu WJ, Zhang BC, Guo R, et al. Renoprotective effect of alprostadil in combination with statins in patients with mild to moderate renal failure undergoing coronary angiography. Chin Med J (Engl). 2013;126(18):3475-80. PMID: 24034093.

Inoue H, Aihara M, Tomioka M, et al. Specific enhancement of vascular endothelial growth factor (VEGF) production in ischemic region by alprostadil--potential therapeutic application in pharmaceutical regenerative medicine. J Pharmacol Sci. 2013;122(2):158-61. PMID: 23728380.

Custom Order

Name*
First Last
Company/Institution
Email*
Enter Email Confirm Email
Product ID
Product Name
Unit Size
Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
Unit Label
Quantity
Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
Comments
Name
This field is for validation purposes and should be left unchanged.

Prostaglandin E1

Quicklinks

Description

Product Info

Shipping and Storage

Downloads

References

Custom Order

Related Products

Piperacillin

Cytochalasin A

Delta Sleep Inducing Peptide

Etoricoxib

Epigallocatechin Gallate

Filipin Complex

Theaflavin

WIN 55,212-2 Mesylate

D,L-Naproxen

Clofibric Acid

MRTX1719

Peimine

Dehydroandrographolide

Deoxyandrographolide

α-Zearalanol

Amyloid-β (25-35)

Rutin Hydrate

Tenovin-6

Rimonabant Hydrochloride

Ginkgolide J

Footer