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Prulifloxacin

Product ID P7082
Cas No. 123447-62-1
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $42.40 Please Inquire
100 mg $68.00 Please Inquire
500 mg $297.30 Please Inquire
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  • Product Info
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  • References
  • Description
  • Product Info
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  • Downloads
  • References
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Description

Prulifloxacin is a fluoroquinolone antibiotic with broad spectrum antibacterial activity against Escherichia, Proteus, Staphylococcus, Streptococcus, and Haemophilus. Like other fluoroquinolones, prulifloxacin inhibits DNA gyrase and topoisomerase IV, preventing DNA synthesis, repair, and transcription. Clinically, prulifloxacin is used to treat infections of the respiratory system and urinary tract.

Product Info

Cas No.

123447-62-1

Purity

≥98%

Formula

C21H20FN3O6S

Formula Wt.

461.46

Chemical Name

1H,4H-(1,3)Thiazeto(3,2-a)quinoline-3-carboxylic acid, 6-fluoro-1-methyl-7-(4-((5-methyl-2-oxo-1,3-dioxol-4- yl)methyl)-1-piperazinyl)-4-oxo-

IUPAC Name

6-fluoro-1-methyl-7-[4-[(5-methyl-2-oxo-1, 3-dioxol-4-yl)methyl]piperazin-1-yl]-4-oxo-1H-[1,3]thiazeto[3, 2-a]quinoline-3-carboxylic acid

Synonym

(+-)-7-(4-((Z)-2,3-Dihydroxy-2-butenyl)-1-piperazinyl)-6-fluoro-1-methyl-4-oxo-1H,4H-(1,3)thiazeto(3,2-a)quinoline-3-carboxylic acid, cyclic carbonate

Solubility

soluble in 0.1 mol/L NaOH,slightly soluble in acetonitrile and glacial acetic acid£¨practically insoluble in water,methanol ethanol and 0.1mol £ØL HCL£ª

Appearance

Yellowish Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

P7082 MSDS PDF

Info Sheet

P7082 Info Sheet PDF

References

Karageorgopoulos DE, Maraki S, Vatopoulos AC, et al. Antimicrobial activity of prulifloxacin in comparison with other fluoroquinolones against community-acquired urinary and respiratory pathogens isolated in Greece. Eur J Clin Microbiol Infect Dis. 2013 Nov;32(11):1417-22. PMID: 23686506.

Castora FJ, Vissering FF, Simpson MV. The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria. Biochim Biophys Acta. 1983 Sep 9;740(4):417-27. PMID: 6309236.

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