Description
PF-06873600 is a selective inhibitor of CDK2/4/6 in multiple in vivo tumor models.
Product Unit Size | Cost | Quantity | Stock |
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PF-06873600 is a selective inhibitor of CDK2/4/6 in multiple in vivo tumor models.
Cas No. | 2185857-97-8 |
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Purity | ≥98% |
Formula | C20H27F2N5O4S |
Formula Wt. | 471.52 |
Synonym | PF06873600, Ebvaciclib |
Appearance | White powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet |
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Freeman-Cook K, Hoffman R, Miller N, et al. Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor. Cancer Cell. 2021 Oct 11;39(10):1404-1421. PMID: 34520734
Jeselsohn R, Schiff R, Grinshpun A. Restoring order at the cell cycle border: co-targeting CDK4/6 and CDK2. Cancer Cell. 2021 Oct 11;39(10):1302-1305. PMID: 34506738
Freeman-Cook K, Hoffman R, Behenna D, et al. Discovery of PF-06873600, a CDK2/4/6 inhibitor for the treatment of cancer. J Med Chem. 2021 Jul 8;64(13):9056-9077. PMID: 34110834