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Gatifloxacin Sesquihydrate

Product ID G0278
Cas No. 180200-66-2
Purity ≥98%
Product Unit SizeCostQuantityStock
500 mg $64.90 In stock
1 g $101.80 In stock
5 g $285.00 In stock
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  • Description
  • Product Info
  • Shipping and Storage
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  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Gatifloxacin is a fluoroquinolone antibiotic that inhibits DNA gyrase. Gatifloxacin exhibits antibacterial efficacy against Mycobacterium and Streptococcus, treating tuberculosis and pneumonia.

Product Info

Cas No.

180200-66-2

Purity

≥98%

Formula

(C19H22FN3O4)2 • (H2O)3

Formula Wt.

402.42

Chemical Name

1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid

IUPAC Name

1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4- oxoquinoline-3-carboxylic acid

Synonym

Tequin

Melting Point

162°C

Solubility

Soluble in water (40-60 mg/mL) at a pH of 2 to 5.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

G0278 MSDS PDF

Info Sheet

G0278 Info Sheet PDF

References

Pantel A, Petrella S, Veziris N, et al. Extending the definition of the GyrB quinolone resistance-determining region in Mycobacterium tuberculosis DNA gyrase for assessing fluoroquinolone resistance in M. tuberculosis. Antimicrob Agents Chemother. 2012 Apr;56(4):1990-6. PMID: 22290942.

Croisier D, Etienne M, Piroth L, et al. In vivo pharmacodynamic efficacy of gatifloxacin against Streptococcus pneumoniae in an experimental model of pneumonia: impact of the low levels of fluoroquinolone resistance on the enrichment of resistant mutants. J Antimicrob Chemother. 2004 Sep;54(3):640-7. PMID: 15317743.

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