LKT Labs

Biochemicals for Life Science Research

Quinapril Hydrochloride

Quinapril Hydrochloride

Product ID Q8134
Cas No. 82586-55-8
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $96.00 In stock
500 mg $287.00 In stock
1 g $458.00 In stock
Bulk Quote

Quicklinks

Description

Quinapril is an angiotensin II-converting enzyme (ACE) inhibitor that exhibits antihypertensive, anti-inflammatory, and cardioprotective activities; it is clinically used to treat hypertension and congestive heart failure. Quinapril decreases levels of aldosterone and increases excretion of Na+. In animal models, quinapril decreases activity of matrix metalloproteinase 2 (MMP2), suppressing left ventricular remodeling. Additionally, this compound decreases expression of pro-inflammatory cytokines in animal models of heart failure.

Product Info

Cas No.

82586-55-8
Purity

≥98%
Formula

C25H30N2O5 • HCl
Formula Wt.

474.99
Chemical Name

(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
IUPAC Name

(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
Synonym

Accupril, Accuprin, Accupro, Acequin, Acuitel, Korec, Quinazil
Melting Point

120-130°C
Solubility

Soluble in water (31mg/mL).
Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

Q8134 MSDS PDF
Info Sheet

Q8134 Info Sheet PDF

References

Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • F5870

    N-formyl-Met-Leu-Phe

    Peptide, involved in neutrophil activation; FPR...

    ≥95%
  • A5228

    Angiogenin

    Small protein, cleaves RNA.

    ≥98%
  • A4926

    AMG-458

    c-MET inhibitor.

    ≥98%
  • P2012

    PF-04217903

    Triazolopyrazine; c-MET inhibitor.

    ≥98%
  • I4962

    Isoimperatorin

    Furocoumarin; COX-2 inhibitor.

    ≥98%
  • A5272

    Angiotensin, dog/rat

    Peptide, derivative of AT I, cleavage product o...

    ≥95%
  • B5561

    B-type Natriuretic Peptide (1-32), human

    Endogenous cardiomodulatory peptide; NPR-A agon...

    ≥97%
  • M0172

    Mastoparan

    Antimicrobial peptide found in Vespula lewisii,...

    ≥95%
  • T1853

    Tenovin-6

    SIRT1/2 inhibitor, indirect p53 activator.

    ≥98%
  • G0248

    (-)-Gambogic Acid

    Xanthone found in Garcinia hanburyi.

    ≥99%
  • M185777

    4-(Methylsulfinyl) butylamine

    ≥99%
  • D183734

    7-O-Desmethyl Rapamycin

    Rapamycin impurity

    ≥85%
  • S3470

    Sirtinol

    Sirtuin inhibitor and iron chelator.

    ≥98%
  • A9914

    AZD-8055

    mTOR inhibitor.

    ≥98%
  • A0819

    Acetylsalicylic Acid

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • G3456

    Ginsenoside Rd

    Triterpene saponin found in species of Panax; 2...

    ≥98%
  • A0963

    Adrenocorticotropic Hormone (1-10), human

    Endogenous peptide hormone fragment, involved i...

    ≥95%
  • A5001

    Aminopterin

    Folic acid analog, derivative of pterin; dihydr...

    ≥98%
  • T0008

    Tacrolimus

    Calcineurin inhibitor.

    ≥98%
  • A2077

    Afatinib

    EGFR inhibitor.

    ≥98%