LKT Labs

Biochemicals for Life Science Research

Quinapril Hydrochloride

Quinapril Hydrochloride

Product ID Q8134
Cas No. 82586-55-8
Purity ≥98%
Product Unit SizeCostQuantityStock
100 mg $96.00 In stock
500 mg $286.70 In stock
1 g $458.20 In stock
Bulk Quote

Quicklinks

Description

Quinapril is an angiotensin II-converting enzyme (ACE) inhibitor that exhibits antihypertensive, anti-inflammatory, and cardioprotective activities; it is clinically used to treat hypertension and congestive heart failure. Quinapril decreases levels of aldosterone and increases excretion of Na+. In animal models, quinapril decreases activity of matrix metalloproteinase 2 (MMP2), suppressing left ventricular remodeling. Additionally, this compound decreases expression of pro-inflammatory cytokines in animal models of heart failure.

Product Info

Cas No.

82586-55-8
Purity

≥98%
Formula

C25H30N2O5 • HCl
Formula Wt.

474.99
Chemical Name

(3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3- phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride
IUPAC Name

(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -3,4-dihydro-1H-isoquinoline-3-carboxylic acid;hydrochloride
Synonym

Accupril, Accuprin, Accupro, Acequin, Acuitel, Korec, Quinazil
Melting Point

120-130°C
Solubility

Soluble in water (31mg/mL).
Appearance

White crystalline powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

Q8134 MSDS PDF
Info Sheet

Q8134 Info Sheet PDF

References

Brower GL, Levick SP, Janicki JS. Inhibition of matrix metalloproteinase activity by ACE inhibitors prevents left ventricular remodeling in a rat model of heart failure. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H3057-64. PMID: 17308006.

We GC, Siroi MG, Qu R, et al. Effects of quinapril on myocardial function, ventricular remodeling and cardiac cytokine expression in congestive heart failure in the rat. Cardiovasc Drugs Ther. 2002 Jan;16(1):29-36. PMID: 12085975.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • L930280

    LXH254

    pan-RAF inhibitor

    ≥99%
  • A0978

    Actinonin

    Peptide deformylase, MMP meprin A, aminopeptida...

    ≥98%
  • C9613

    Cyclosporin D

    Cyclosporin metabolite; weak calmodulin inhibit...

    ≥98%
  • C577524

    Concanamycin A

    Macrolide lactone antibiotic.

    ≥98%
  • B8144

    Bulleyaconitine A

    Found in Aconitum bulleyanum; voltage-gated Na+...

    ≥95%
  • A5301

    Anacetrapib

    Cholesterol ester transfer protein inhibitor.

    ≥98%
  • R8076

    Rutin Hydrate

    Flavonoid glycoside found in fruit, asparagus, ...

    ≥95%
  • D022705

    Darunavir

    HIV and AIDS

    ≥99%
  • A686164

    Arecaidine Hydrochloride

    mAChR agonist, selective for M2.

    ≥98%
  • B8277

    Butein

    Flavonoid found in Rhus verniciflua and Butea m...

    ≥99%
  • I5215

    Indolicidin

    Antimicrobial peptide.

    ≥95%
  • P4780

    Plumbagin

    Naphthoquinone found in Plumbago.

    ≥98%
  • Z4833

    ZM-336372

    c-Raf inhibitor, tyrosine kinase inhibitor.

    ≥98%
  • D0263

    Dapoxetine Hydrochloride

    SERT inhibitor, potential voltage-gated K+ chan...

    ≥99%
  • G7340

    GSK-126

    EZH2 HMT inhibitor.

    ≥98%, ≥99%ee
  • P2858

    4-α-Phorbol-12-myristate-13-acetate

    Negative control for PKC activation.

    ≥98%
  • P698583

    Prostaglandin E2

    principal metabolic product of COX-2

    ≥98%
  • A985132

    AZD-8186

    Selective inhibitor of PI3Kβ and PI3Kδ.

    ≥99%
  • T0100

    10-Deacetyltaxol

    Taxane found in Taxus; microtubule depolymeriza...

    ≥98%
  • N7604

    Naltriben

    δ2OR antagonist.

    ≥95%