LKT Labs

Biochemicals for Life Science Research

(R)-Synephrine

(R)-Synephrine

Product ID S9755
Cas No. 614-35-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $45.80 In stock
5 g $64.50 In stock
25 g $214.60 In stock
Bulk Quote

Quicklinks

Description

Synephrine is an endogenous alkaloid that can also be found in citrus fruits, Evodia, and Zanthoxylum. Synephrine exhibits vasoconstrictive, anti-inflammatory, antibacterial, and gastrointestinal motility modulating activities. Synephrine acts as a positive inotrope, activating adrenergic receptors (displaying partial selectivity for α-adrenergic receptors), TAAR-1 receptors, and 5-HT receptors. Synephrine decreases levels of ROS, activity of myeloperoxidase, infiltration of inflammatory cells, and expression of TNF-α and IL-6 in the lungs of animal models of lung injury and inflammation. Additionally, synephrine inhibits gastrointestinal motility and slows gastric emptying.

Product Info

Cas No.

614-35-7
Purity

≥98%
Formula

C9H13NO2
Formula Wt.

167.21
IUPAC Name

[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium
Synonym

R(-)-Synephrine; D-(-)-Synephrine; (-)-Oxedrine
Melting Point

162-164°C
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

S9755 MSDS PDF
Info Sheet

S9755 Info Sheet PDF

References

Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • R0253

    Ranitidine Hydrochloride

    Histamine H2 inverse agonist.

    ≥98%
  • F4483

    Flufenamic Acid

    NSAID; TREK1 K+ potentiator, voltage-gated Na+ ...

    ≥97%
  • P1853

    Penicillin V Potassium

    Hydrophobic β-lactam; penicillin binding prote...

    ≥98%
  • S7601

    Statil

    Aldose reductase inhibitor.

    ≥98%
  • A4444

    L-Alliin

    Cysteine derivative found in Allium; NMDA NR2A/...

    ≥98%
  • B8174

    Butylated Hydroxyanisole

    Commercial food additive, antioxidant.

    ≥96%
  • L1884

    Levosimendan

    Ca2+ sensitizer; ATP-sensitive K+ channel activ...

    ≥98%
  • M1575

    7-Methyl-6-mercaptopurine

    Thiopurine antimetabolite; PRPP amidotransferas...

    ≥87%
  • I7259

    Isoproterenol Hydrochloride

    β-adrenergic agonist.

    ≥98%
  • A9710

    AZD-2014

    mTOR inhibitor.

    ≥98%
  • G5322

    GNF-5

    Abl inhibitor.

    ≥99%
  • H1992

    Hexaconazole

    Triazole; demethylation inhibitor.

    ≥95%
  • P1849

    Pemetrexed Disodium

    Thymidylate synthase inhibitor, potential SHMT,...

    ≥98%
  • C7098

    Crystalline peptide

    Dipeptide.

    ≥95%
  • D1749

    Demecolcine

    Used to study embryonic cloning; microtubule po...

    ≥97%
  • A7034

    Aripiprazole

    D2 and 5-HT1A partial agonist, 5-HT2C/6/7 antag...

    ≥98%
  • L1616

    LEE-011

    CDK4/6 inhibitor.

    ≥98%
  • F4518

    Fleroxacin

    Fluoroquinolone; bacterial DNA gyrase and helic...

    ≥98%
  • G016499

    2’,3’-cGAMP Sodium Salt

    Agonist of STING.

    ≥99%
  • P1761

    Pepstatin

    Aspartyl protease inhibitor.

    ≥98%