LKT Labs

Biochemicals for Life Science Research

(R)-Synephrine

(R)-Synephrine

Product ID S9755
Cas No. 614-35-7
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $45.80 In stock
5 g $64.50 In stock
25 g $214.60 In stock
Bulk Quote

Quicklinks

Description

Synephrine is an endogenous alkaloid that can also be found in citrus fruits, Evodia, and Zanthoxylum. Synephrine exhibits vasoconstrictive, anti-inflammatory, antibacterial, and gastrointestinal motility modulating activities. Synephrine acts as a positive inotrope, activating adrenergic receptors (displaying partial selectivity for α-adrenergic receptors), TAAR-1 receptors, and 5-HT receptors. Synephrine decreases levels of ROS, activity of myeloperoxidase, infiltration of inflammatory cells, and expression of TNF-α and IL-6 in the lungs of animal models of lung injury and inflammation. Additionally, synephrine inhibits gastrointestinal motility and slows gastric emptying.

Product Info

Cas No.

614-35-7
Purity

≥98%
Formula

C9H13NO2
Formula Wt.

167.21
IUPAC Name

[(2R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl]-methylazanium
Synonym

R(-)-Synephrine; D-(-)-Synephrine; (-)-Oxedrine
Melting Point

162-164°C
Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient
Ship Temp

Ambient

Downloads

MSDS

S9755 MSDS PDF
Info Sheet

S9755 Info Sheet PDF

References

Wu Q, Li R, Soromou LW, et al. p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway. Inflamm Res. 2014 Jun;63(6):429-39. PMID: 24487736.

Ozçelik B, Kartal M, Orhan I. Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids. Pharm Biol. 2011 Apr;49(4):396-402. PMID: 21391841.

Fang YS, Shan DM, Liu JW, et al. Effect of constituents from Fructus Aurantii Immaturus and Radix Paeoniae Alba on gastrointestinal movement. Planta Med. 2009 Jan;75(1):24-31. PMID: 19016407.

Endoh M, Schümann HJ, Krappitz N, et al. alpha-Adrenoceptors mediating positive inotropic effects on the ventricular myocardium: some aspects of structure-activity relationship of sympathomimetic amines. Jpn J Pharmacol. 1976 Apr;26(2):179-90. PMID: 7694.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S6232

    Spiramycin

    Macrolide; protein synthesis inhibitor. ≥3900...

    ≥3900 IU/mg
  • I0518

    I-BET-762

    BRD inhibitor.

    ≥98%
  • M1649

    Melanoma-associated Antigen Peptide 1 (27-35), human

    Melanoma-associated antigen.

    ≥95%
  • N4972

    NMS-873

    Valosin-containing protein inhibitor.

    ≥98%
  • N5768

    Norfloxacin

    Fluoroquinolone; topoisomerase IV and bacterial...

    ≥98%
  • A0802

    Acarbose

    α-glucosidase inhibitor.

    ≥98%
  • F0150

    Famotidine

    Histamine H2 antagonist, GSK-3β inhibitor.

    ≥98%
  • V0273

    Vasoactive Intestinal Peptide

    Endogenous peptide hormone, involved in enteric...

    ≥95%
  • O4578

    Oltipraz

    Antioxidant; Nrf2 activator.

    ≥98%
  • L283080

    LHC-165

    TLR7 agonist

    ≥99%
  • P8370

    Purmorphamine

    Hedgehog and Smo agonist.

    ≥98%
  • B6816

    Brefeldin A

    Lactone found in fungi such as Eupenicillium; g...

    ≥97%
  • K9858

    Kyotorphin

    Opioid neuropeptide; kyotorphin agonist.

    ≥95%
  • P2817

    Phentolamine Hydrochloride

    ATP-sensitive K+ channel activator, α-adrenerg...

    ≥98%
  • D1627

    Dehydrocostus Lactone

    Sesquiterpene lactone found in Saussurea.

    ≥98%
  • H5750

    Homoharringtonine

    Alkaloid found in Cephalotaxus; ribosomal prote...

    ≥97%
  • N1982

    Neuromedin U, rat

    Endogenous neuropeptide, involved in energy hom...

    ≥95%
  • R0247

    Raltegravir

    HIV integrase inhibitor.

    ≥99%
  • T503720

    TMS

    Selective inhibitor of cytochrome P450 1B1 (CYP...

    ≥99%
  • A7071

    Atriopeptin II, rat/rabbit/mouse

    ANP analog, cardiomodulatory peptide; NPR-A ago...

    ≥95%