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Ranitidine Hydrochloride

Ranitidine Hydrochloride

Product ID R0253
Cas No. 66357-59-3
Purity ≥98%
Product Unit SizeCostQuantityStock
1 g $41.80 In stock
5 g $116.70 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ranitidine is an inverse agonist at H2 histamine receptors, inducing receptor desensitization and inhibiting downstream signaling. Ranitidine displays antacid activity and is clinically used to treat peptic ulcer disease and gastroesophageal reflux disease (GERD).

Product Info

Cas No.

66357-59-3

Purity

≥98%

Formula

C13H22N4O3S • HCl

Formula Wt.

350.86

Chemical Name

N-[2-[[[-5-[(Dimethylamino)methyl]-2-furanyl]- methyl]thio]ethyl]-N'-methyl-2-nitro-1,1-ethenediamine

IUPAC Name

(E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]- 1-N-methyl-2-nitroethene-1,1-diamine;hydrochloride

Synonym

Azantac, Melfax, Noctone, Ranidil, Taural, Trigger, Ulcex, Zantac, Zantic

Melting Point

133-134°C

Solubility

Soluble in acetic acid, water and methanol. Slightly soluble in ethanol. Practically insoluble in chloroform.

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R0253 MSDS PDF

Info Sheet

R0253 Info Sheet PDF

References

Alonso N, Monczor F, Echeverría E, et al. Signal transduction mechanism of biased ligands at histamine H2 receptors. Biochem J. 2014 Apr 1;459(1):117-26. PMID: 24417223.

Rodriguez-Stanley S, Ciociola AA, Zubaidi S, et al. A single dose of ranitidine 150 mg modulates oesophageal acid sensitivity in patients with functional heartburn. Aliment Pharmacol Ther. 2004 Nov 1;20(9):975-82. PMID: 15521845.

Custom Order

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  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

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