• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ranolazine Dihydrochloride

Ranolazine Dihydrochloride

Product ID R0154
Cas No. 95635-56-6
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $97.70 In stock
100 mg $180.30 In stock
500 mg $578.40 In stock
1 g $976.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ranolazine exhibits anti-anginal, anti-arrhythmic, and cardioprotective activities; it is clinically used to treat angina pectoris. Ranolazine inhibits the late Na+ current (Nav1.7 and Nav1.7 channels) and subsequent intracellular Ca2+ accumulation. In hypertensive rats, ranolazine decreases end diastolic pressure, improving diastolic function and decreasing free Ca2+ levels. In other animal models, ranolazine inhibits induction of atrial flutter and atrial fibrillation.

Product Info

Cas No.

95635-56-6

Purity

≥98%

Formula

C24H33N3O4 • 2HCl

Formula Wt.

500.47

Chemical Name

N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride

IUPAC Name

N-(2, 6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin- 1-yl]acetamide;dihydrochloride

Synonym

RS-43285

Melting Point

164-166°C

Solubility

Soluble in water.

Appearance

A White or Almost White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R0154 MSDS PDF

Info Sheet

R0154 Info Sheet PDF

References

Sobky S, Fawzy I, Ahmed M, et al. Drug repurposing of argatroban, glimepiride, and ranolazine shows anti-SARS-CoV-2 activity via diverse mechanisms. Heliyon. 2025 Jan 10;11(3):e41894. PMID: 39968139.

Tocchetti CG, Carpi A, Coppola C, et al. Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. Eur J Heart Fail. 2014 Jan 6. [Epub ahead of print]. PMID: 24464789.

Aldakkak M, Stowe DF, Camara AK. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14. PMID: 24574825.

Aidonidis I, Doulas K, Hatziefthimiou A, et al. Ranolazine-induced postrepolarization refractoriness suppresses induction of atrial flutter and fibrillation in anesthetized rabbits. J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):94-101. PMID: 22872232.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S7769

    Streptomycin Sulfate

    Aminoglycoside; protein translation inhibitor, ...

    ≥98%
  • E6257

    Epothilone B

    Microtubule depolymerization inhibitor.

    ≥98%
  • C281006

    Chaetocin

    Chaetocin is naturally produced by Chaetomium s...

    ≥98%
  • M002698

    M2698

    Dual inhibitor of p70S6K and Akt.

    ≥99%
  • H9815

    25-Hydroxyvitamin D3

    Vitamin D, calcitriol prodrug; VDR agonist.

    ≥98%
  • N1721

    Nefiracetam

    Pyrrolidone; NMDA and mGluR5 agonist, N-type an...

    ≥98%
  • A8070

    Auraptene

    Monoterpene coumarin ether found in Citrus; PPA...

    ≥98%
  • V9200

    VX-950

    NS3/4A serine protease inhibitor.

    ≥98%
  • M1605

    Mebendazole

    Benzimidazole; microtubule polymerization inhib...

    ≥98%
  • P7058

    Protocatechuic Aldehyde

    Polyphenol found in various plants and foods.

    ≥98%
  • I5072

    Imazalil

    Triazole; 14-α demethylase and aromatase inhib...

    ≥95%, titration; ≥70%, HPLC
  • E9416

    Exendin-3

    Peptide, GLP-1 analog found in Heloderma; GLP-1...

    ≥95%
  • M1708

    Mecamylamine Hydrochloride

    Monoterpene; nAChR antagonist.

    ≥98%
  • SB5778

    Snake venom – Bothrops neuwiedi diporous

    Snake venom found in Bothrops neuwiedi diporus;...

    ≥98%
  • P0049

    Pamidronate Disodium Pentahydrate

    Bisphosphonate.

    ≥98%
  • N6076

    N(p-Tosyl)-GPR-pNA

    Thrombin substrate used to measure thrombin act...

    ≥95%
  • J6400

    (+)-JQ-1

    Triazolothienodiazepine; BRD inhibitor.

    ≥99%
  • C6019

    C-Peptide, human

    Endogenous peptide, connects A and B chains of ...

    ≥95%
  • L930280

    LXH254

    pan-RAF inhibitor

    ≥99%
  • G1210

    GDC-0623

    MEK inhibitor.

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only