• Skip to primary navigation
  • Skip to main content
  • Skip to footer

LKT Labs

Biochemicals for Life Science Research

  • Products
    • New Products
    • Cancer Biology
    • Cardiovascular
    • Endocrine Signaling and Immunology
    • Metabolic and GI Pathology
    • Microbiology
    • Natural Products
    • Neuroscience
    • Peptides
    • Pharmaceutical Impurities and Derivatives
    • Stem Cell Modulators
  • Services
    • Custom Synthesis
    • Natural Product Isolation
    • Analytical Services
  • Int’l Distributors
  • Support
    • About LKT Labs
    • General Inquiry
    • Bulk Quote Request
    • Document Request
    • Technical Support
    • Catalog Request
    • Product Flyers
  • Contact Us
  • Cart
  • Login / Register
Ranolazine Dihydrochloride

Ranolazine Dihydrochloride

Product ID R0154
Cas No. 95635-56-6
Purity ≥98%
Product Unit SizeCostQuantityStock
25 mg $97.70 In stock
100 mg $180.30 In stock
500 mg $578.40 In stock
1 g $976.50 In stock
Bulk Quote

Quicklinks

  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References
  • Custom Order

Description

Ranolazine exhibits anti-anginal, anti-arrhythmic, and cardioprotective activities; it is clinically used to treat angina pectoris. Ranolazine inhibits the late Na+ current (Nav1.7 and Nav1.7 channels) and subsequent intracellular Ca2+ accumulation. In hypertensive rats, ranolazine decreases end diastolic pressure, improving diastolic function and decreasing free Ca2+ levels. In other animal models, ranolazine inhibits induction of atrial flutter and atrial fibrillation.

Product Info

Cas No.

95635-56-6

Purity

≥98%

Formula

C24H33N3O4 • 2HCl

Formula Wt.

500.47

Chemical Name

N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride

IUPAC Name

N-(2, 6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin- 1-yl]acetamide;dihydrochloride

Synonym

RS-43285

Melting Point

164-166°C

Solubility

Soluble in water.

Appearance

A White or Almost White Crystalline Powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

R0154 MSDS PDF

Info Sheet

R0154 Info Sheet PDF

References

Sobky S, Fawzy I, Ahmed M, et al. Drug repurposing of argatroban, glimepiride, and ranolazine shows anti-SARS-CoV-2 activity via diverse mechanisms. Heliyon. 2025 Jan 10;11(3):e41894. PMID: 39968139.

Tocchetti CG, Carpi A, Coppola C, et al. Ranolazine protects from doxorubicin-induced oxidative stress and cardiac dysfunction. Eur J Heart Fail. 2014 Jan 6. [Epub ahead of print]. PMID: 24464789.

Aldakkak M, Stowe DF, Camara AK. Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. Clin Med Insights Ther. 2013 Jan 15;2013(5):1-14. PMID: 24574825.

Aidonidis I, Doulas K, Hatziefthimiou A, et al. Ranolazine-induced postrepolarization refractoriness suppresses induction of atrial flutter and fibrillation in anesthetized rabbits. J Cardiovasc Pharmacol Ther. 2013 Jan;18(1):94-101. PMID: 22872232.

Custom Order

  • Size of single unit expressed as number (e.g. '500' in the case of 500 mg)
  • Total quantity of unit size desired (e.g. '10' in the case of 10 x 500 mg). If only one unit is desired, you may leave this blank.
  • This field is for validation purposes and should be left unchanged.

Related Products

  • S0244

    Salsalate

    Salicylic acid prodrug, NSAID; weak COX-1/2 inh...

    ≥95%
  • V574451

    Volitinib

    c-Met inhibitor.

    ≥98%
  • A4400

    Alamethicin

    Antimicrobial peptide found in Trichoderma, ind...

    ≥95%
  • W0274

    S-(−)-Warfarin Sodium >99%ee

    Coumarin, more potent isomer; VKORC1 inhibitor....

    ≥99%
  • I2056

    Ifosfamide

    Nitrogen mustard, DNA alkylator.

    ≥98%
  • T1012

    13-TES-Baccatin III

    Synthesis impurity

    ≥98%
  • F5766

    Forchlorfenuron

    Synthetic cytokinin, plant growth regulator; fi...

    ≥98%
  • H1794

    Hexamethonium Bromide Hydrate

    Non-depolarizing NMJ blocker; nAChR antagonist....

    ≥98%
  • M0113

    Madecassoside

    Triterpenoid found in Centella.

    ≥90%
  • F4581

    5-Fluorocytosine

    Synthetic antifungal.

    ≥98%
  • Z5645

    Zoledronate Disodium Tetrahydrate

    Bisphosphonate; FPPS inhibitor.

    ≥98%
  • G3254

    10-Gingerol

    Phenol found in Zingiber; 5-HT3 antagonist.

    ≥99%
  • C451338

    Clioquinol

    Antifungal agent with neuroprotective activity....

    ≥98%
  • I525138

    Indoximod

    Indoleamine 2,3-dioxygenase inhibitor.

    ≥98%
  • P3269

    Piroxicam

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • R2511

    RGDC

    Peptide, used to study cell-surface binding; po...

    ≥95%
  • C2818

    Chelerythrine Chloride

    benzophenanthridine alkaloid found in Chelidoni...

    ≥98%
  • F1652

    Fenbufen

    NSAID; COX-1/2 inhibitor.

    ≥98%
  • G4535

    Glimepiride

    Sulfonylurea; ATP-sensitive K+ channel blocker....

    ≥98%
  • O2146

    R-(+)-Ofloxacin

    Fluoroquinolone, optically active isomer of ofl...

    ≥98%

Footer

  • Contact Us
  • About Us
  • Site Map
  • Terms and Conditions
LKT Laboratories, Inc.
545 Phalen Blvd.
St. Paul MN, 55130

Ph: (888)-558-5227
Fax: (888)-558-7329

©2025 LKT Laboratories, All Rights Reserved - Products for research use only